DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT3G18840

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_001078182.2	Gene:	AT3G18840 / 821417	AraportID:	AT3G18840	Length:	678	Species:	Arabidopsis thaliana

Alignment Length:	571	Identity:	120/571 - (21%)
Similarity:	187/571 - (32%)	Gaps:	196/571 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 IKDHLKANRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKA-GYTRKAFFLYTKMRQR---G 214
            |..::|.|.:.||     :.:.:.|..:.|...||.|:||.||. |...:|..::.:|.::   .
plant    61 IAAYVKFNNVKEA-----RELFESDNCERDLITYNTLLSGFAKTDGCESEAIEMFGEMHRKEKDD 120

  Fly   215 LQVTGGTYTSLFNACANAPSV--------------SDGLAKAQILRENMLEK-GYEPNVKNY--- 261
            :.:...|.|::....|...:|              :||...|.....:|..| |....|.|.
plant   121 IWIDDFTVTTMVKLSAKLTNVFYGEQLHGVLVKTGNDGTKFAVSSLIHMYSKCGKFKEVCNIFNG 185

  Fly   262 -----------NAMIKAYGRCGDVDTAYMLADEMMERQLELNADT--FNFLLQACASN--SEHGF 311
                       ||||.||.|.||:|.|.    .:..|..||| ||  :|.|:...|.|  .|...
plant   186 SCVEFVDSVARNAMIAAYCREGDIDKAL----SVFWRNPELN-DTISWNTLIAGYAQNGYEEEAL 245

  Fly   312 RHALLTWHNMLQRGISPDYYSFNAMLRC--------------AR--------------------- 341
            :.|:    :|.:.|:..|.:||.|:|..              ||
plant   246 KMAV----SMEENGLKWDEHSFGAVLNVLSSLKSLKIGKEVHARVLKNGSYSNKFVSSGIVDVYC 306

  Fly   342 DC-------------GFGDLDSMREVIDKIAPSAARKKPVLQLEKGQQDDLPSVEANT--TTLPA 391
            .|             |||:|.|...:|                 .|.......|||..  .:|..
plant   307 KCGNMKYAESAHLLYGFGNLYSASSMI-----------------VGYSSQGKMVEAKRLFDSLSE 354

  Fly   392 QIEVATTASELELPNLLLPQP--HLGSLVALEEVTRPHERFL--LLG--GLTGFLE-------HM 443
            :..|..||..|...||..|..  .|.......|...|....:  :||  .|..::|       |.
plant   355 KNLVVWTAMFLGYLNLRQPDSVLELARAFIANETNTPDSLVMVSVLGACSLQAYMEPGKEIHGHS 419

  Fly   444 KQHNITPDIETFTAMLEVIPPTNAAEKQLLTFVRKI---GLKADIDFFNILI--------KKRSM 497
            .:..|..|.:..||.:::.......|     :..:|   ..:.|...:|.:|        :.:|.
plant   420 LRTGILMDKKLVTAFVDMYSKCGNVE-----YAERIFDSSFERDTVMYNAMIAGCAHHGHEAKSF 479

  Fly   498 RFDYESAKEVLLMIRTAGLRPDIVTYGVLALGCRTQ----------------------------- 533
            : .:|...|       .|.:||.:|:..|...||.:
plant   480 Q-HFEDMTE-------GGFKPDEITFMALLSACRHRGLVLEGEKYFKSMIEAYNISPETGHYTCM 536

  Fly   534 ----------EEARELLEQMHVAGIKMNMPILGAMLRQGCANKSFSYVNEI 574
                      ::|.||:|  .:..::.:..||||.|.....||:...|.|:
plant   537 IDLYGKAYRLDKAIELME--GIDQVEKDAVILGAFLNACSWNKNTELVKEV 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	11/38 (29%)
		PPR_2	182..231	CDD:289786	13/52 (25%)
		PPR	185..215	CDD:279828	10/33 (30%)
		PPR repeat	186..213	CDD:276811	10/27 (37%)
		PPR repeat	219..252	CDD:276811	8/46 (17%)
		PPR_1	252..284	CDD:289614	15/46 (33%)
		PPR_2	256..304	CDD:289786	21/63 (33%)
		PPR repeat	258..287	CDD:276811	13/42 (31%)
		PPR repeat	293..324	CDD:276811	9/34 (26%)
		PPR repeat	330..357	CDD:276811	13/74 (18%)
		PPR repeat	485..514	CDD:276811	5/36 (14%)
		PPR repeat	552..576	CDD:276811	9/23 (39%)
AT3G18840	NP_001078182.2	PPR	24..54	CDD:279828
		PPR repeat	25..52	CDD:276811
		PPR_2	53..98	CDD:289786	12/41 (29%)
		PPR repeat	54..80	CDD:276811	5/23 (22%)
		PPR_1	80..113	CDD:289614	11/32 (34%)
		PPR repeat	86..116	CDD:276811	10/29 (34%)
		PPR repeat	164..189	CDD:276811	5/24 (21%)
		PPR_2	192..237	CDD:289786	19/49 (39%)
		PPR repeat	193..222	CDD:276811	12/32 (38%)
		PPR	<197..216	CDD:295754	11/22 (50%)
		PPR_2	224..270	CDD:289786	15/49 (31%)
		PPR repeat	225..254	CDD:276811	8/32 (25%)
		PPR	226..256	CDD:279828	7/33 (21%)
		PPR repeat	326..355	CDD:276811	8/45 (18%)
		PPR repeat	393..422	CDD:276811	5/28 (18%)
		PPR_2	458..504	CDD:289786	11/53 (21%)
		PPR repeat	461..488	CDD:276811	5/34 (15%)
		PPR repeat	494..523	CDD:276811	4/28 (14%)
		PPR repeat	530..554	CDD:276811	3/23 (13%)
		DYW_deaminase	633..>673	CDD:291126
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000