DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4611 and PPR40

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_188314.1	Gene:	PPR40 / 820944	AraportID:	AT3G16890	Length:	659	Species:	Arabidopsis thaliana

Alignment Length:	720	Identity:	147/720 - (20%)
Similarity:	250/720 - (34%)	Gaps:	188/720 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LNATGRRLNSYN---ISRLVILPATWSCSQNRLLHVRITDQQAGLETKREAN--RNQ-NPFREEV 77
            ||::|:..|..|   ||: ||....|..    :|:...|..:.||.|:...:  :|| ||.....
plant    35 LNSSGKPTNPLNQRYISQ-VIERKDWFL----ILNQEFTTHRIGLNTRFVISVLQNQDNPLHSLR 94

  Fly    78 FEELITAAPKEHQKFKPEKKPKEKSTKKVQDFGDPDTFGDAKVAATEDPGDVEEEEFLSNST-RR 141
            |...::       .|.| ...|::|.|.|                            |.|:. |:
plant    95 FYLWVS-------NFDP-VYAKDQSLKSV----------------------------LGNALFRK 123

  Fly   142 SKKLKAVEYARQIKDH------------------------------------------------- 157
            ...|.::|..::|:|.
plant   124 GPLLLSMELLKEIRDSGYRISDELMCVLIGSWGRLGLAKYCNDVFAQISFLGMKPSTRLYNAVID 188

  Fly   158 --LKANRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGG 220
              :|:|.|:  :|.|:.:.::.|..|||::.||:||.|..|.|...:|..|..:|.|.|.:....
plant   189 ALVKSNSLD--LAYLKFQQMRSDGCKPDRFTYNILIHGVCKKGVVDEAIRLVKQMEQEGNRPNVF 251

  Fly   221 TYTSLFNACANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNAMIKAYGRCGDVDTAYMLADEMM 285
            |||.|.:....|..|.:.|.:.:::|...|    .||.......:....||.....|:.:....|
plant   252 TYTILIDGFLIAGRVDEALKQLEMMRVRKL----NPNEATIRTFVHGIFRCLPPCKAFEVLVGFM 312

  Fly   286 ERQLELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLRC-------ARDC 343
            |:...|....::.:|...::||........|  ..:.:||..||..:|||.:.|       ...|
plant   313 EKDSNLQRVGYDAVLYCLSNNSMAKETGQFL--RKIGERGYIPDSSTFNAAMSCLLKGHDLVETC 375

  Fly   344 GFGDLDSMREVIDKIAPSAARKKPVLQLEKGQQDD-----------LPSVEANTTTLPA-----Q 392
            ...|....|.|...........:.:|..::..:.|           |.||.:....:..     :
plant   376 RIFDGFVSRGVKPGFNGYLVLVQALLNAQRFSEGDRYLKQMGVDGLLSSVYSYNAVIDCLCKARR 440

  Fly   393 IE-VATTASELE----LPNLLLPQPHLGSLVALEEVTRPHERFLLLGGLTGFLEHMKQHNITPDI 452
            || .|...:|::    .|||:.....|.......:|.:.|          |.||.:..|...||:
plant   441 IENAAMFLTEMQDRGISPNLVTFNTFLSGYSVRGDVKKVH----------GVLEKLLVHGFKPDV 495

  Fly   453 ETFTAMLEVIPPTNAAEKQLLTFVRKIGLKADIDFFNILIKKRSMRFDYESAKEVLLMIRTAGLR 517
            .||:.::                             |.|.:.:.::..::..||:|    ..|:.
plant   496 ITFSLII-----------------------------NCLCRAKEIKDAFDCFKEML----EWGIE 527

  Fly   518 PDIVTYGVLALGCRT---QEEARELLEQMHVAGIKMNMPILGAMLRQGCANKSFSYVNEIIQLSL 579
            |:.:||.:|...|.:   .:.:.:|..:|...|:..::....|.::..|..:......|:::..|
plant   528 PNEITYNILIRSCCSTGDTDRSVKLFAKMKENGLSPDLYAYNATIQSFCKMRKVKKAEELLKTML 592

  Fly   580 EEGLKPNEAFLRHLHNFHRGCARAIDARHPSTKTAAFKKGHSKFCDKY-RLYYEEQGL--SGLKL 641
            ..||||:......|........|..:||...:..    :.|....|.| :...||..|  |||..
plant   593 RIGLKPDNFTYSTLIKALSESGRESEAREMFSSI----ERHGCVPDSYTKRLVEELDLRKSGLSR 653

  Fly   642 EDAIA 646
            |...|
plant   654 ETVSA 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	14/89 (16%)
		PPR_2	182..231	CDD:289786	18/48 (38%)
		PPR	185..215	CDD:279828	11/29 (38%)
		PPR repeat	186..213	CDD:276811	10/26 (38%)
		PPR repeat	219..252	CDD:276811	9/32 (28%)
		PPR_1	252..284	CDD:289614	5/31 (16%)
		PPR_2	256..304	CDD:289786	9/47 (19%)
		PPR repeat	258..287	CDD:276811	4/28 (14%)
		PPR repeat	293..324	CDD:276811	4/30 (13%)
		PPR repeat	330..357	CDD:276811	8/33 (24%)
		PPR repeat	485..514	CDD:276811	5/28 (18%)
		PPR repeat	552..576	CDD:276811	3/23 (13%)
PPR40	NP_188314.1	PPR repeat	150..174	CDD:276811	0/23 (0%)
		PLN03218	<178..>584	CDD:215636	93/456 (20%)
		PPR repeat	183..209	CDD:276811	5/27 (19%)
		PPR repeat	215..244	CDD:276811	10/28 (36%)
		PPR repeat	250..279	CDD:276811	8/28 (29%)
		PPR repeat	357..384	CDD:276811	6/26 (23%)
		PPR repeat	393..419	CDD:276811	2/25 (8%)
		PPR repeat	427..454	CDD:276811	4/26 (15%)
		PPR repeat	460..489	CDD:276811	7/38 (18%)
		PPR repeat	497..524	CDD:276811	7/59 (12%)
		PPR repeat	530..559	CDD:276811	6/28 (21%)
		PPR_2	563..610	CDD:404055	9/46 (20%)
		PPR repeat	565..593	CDD:276811	3/27 (11%)
		PPR repeat	600..628	CDD:276811	4/31 (13%)
		PPR	601..635	CDD:273253	5/37 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960