DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT3G07290

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_187385.1	Gene:	AT3G07290 / 819917	AraportID:	AT3G07290	Length:	880	Species:	Arabidopsis thaliana

Alignment Length:	614	Identity:	133/614 - (21%)
Similarity:	226/614 - (36%)	Gaps:	160/614 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 AVEYARQIKDHLKANRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMR 211
            :|.|:..|....:..||.||..:.:|  :.|...:|....|.:||......|...|||.|:.:|.
plant   266 SVSYSILIHGLCEVGRLEEAFGLKDQ--MGEKGCQPSTRTYTVLIKALCDRGLIDKAFNLFDEMI 328

  Fly   212 QRGLQVTGGTYTSLFNACANAPSVSDGLAKAQILRE------NMLEKGYEPNVKNYNAMIKAYGR 270
            .||.:....|||.|.          |||.:...:.|      .|::....|:|..|||:|..|.:
plant   329 PRGCKPNVHTYTVLI----------DGLCRDGKIEEANGVCRKMVKDRIFPSVITYNALINGYCK 383

  Fly   271 CGDVDTAYMLADEMMERQLELNADTFNFLLQA-CASNSEHGFRHALLTWHNMLQRGISPDYYSFN 334
            .|.|..|:.|...|.:|..:.|..|||.|::. |.....:...|.|   ..||..|:|||..|:|
plant   384 DGRVVPAFELLTVMEKRACKPNVRTFNELMEGLCRVGKPYKAVHLL---KRMLDNGLSPDIVSYN 445

  Fly   335 AMLRCARD--CGFGDLDSMREVIDK-----IAPSAARKKPV------------------LQLEKG 374
            .::    |  |..|.:::..:::..     |.|.......:                  |.|.||
plant   446 VLI----DGLCREGHMNTAYKLLSSMNCFDIEPDCLTFTAIINAFCKQGKADVASAFLGLMLRKG 506

  Fly   375 -QQDDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPHLGSLVALEEVTRPHERFLLLGGLT- 437
             ..|::    ..||.:....:|..|...|.:         |.:||.:..:|.||...::|..|:
plant   507 ISLDEV----TGTTLIDGVCKVGKTRDALFI---------LETLVKMRILTTPHSLNVILDMLSK 558

  Fly   438 --------GFLEHMKQHNITPDIETFTAMLEVIPPTN--AAEKQLLTFVRKIGLKADIDFFNILI 492
                    ..|..:.:..:.|.:.|:|.:::.:..:.  ....::|..::..|...::..:.|:|
plant   559 GCKVKEELAMLGKINKLGLVPSVVTYTTLVDGLIRSGDITGSFRILELMKLSGCLPNVYPYTIII 623

  Fly   493 KKRSMRFDYESAKEVLLMIRTAGLRPDIVTYGVLALGC-------RTQEEARELLEQMHVAGIKM 550
            .........|.|:::|..::.:|:.|:.|||.|:..|.       |..|..|.::|:    |.::
plant   624 NGLCQFGRVEEAEKLLSAMQDSGVSPNHVTYTVMVKGYVNNGKLDRALETVRAMVER----GYEL 684

  Fly   551 NMPILGAMLRQG---------------------------CANKSFSYV----------------- 571
            |..|..::| ||                           |.|:..|.|
plant   685 NDRIYSSLL-QGFVLSQKGIDNSEESTVSDIALRETDPECINELISVVEQLGGCISGLCIFLVTR 748

  Fly   572 ----------NEIIQLSLEEGLKPNEAFLRHLHNF-----HRGCARAIDARHPSTKTAAFKKGHS 621
                      |:::|..||.|:...:|....:.::     |..|...|.....|....:||
plant   749 LCKEGRTDESNDLVQNVLERGVFLEKAMDIIMESYCSKKKHTKCMELITLVLKSGFVPSFK---- 809

  Fly   622 KFCDKYRLYYEEQGLSGLKLEDAIAKVKE 650
            .||         ..:.|||.|....:.:|
plant   810 SFC---------LVIQGLKKEGDAERARE 829

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	10/38 (26%)
		PPR_2	182..231	CDD:289786	16/48 (33%)
		PPR	185..215	CDD:279828	10/29 (34%)
		PPR repeat	186..213	CDD:276811	9/26 (35%)
		PPR repeat	219..252	CDD:276811	9/38 (24%)
		PPR_1	252..284	CDD:289614	11/31 (35%)
		PPR_2	256..304	CDD:289786	18/48 (38%)
		PPR repeat	258..287	CDD:276811	11/28 (39%)
		PPR repeat	293..324	CDD:276811	9/31 (29%)
		PPR repeat	330..357	CDD:276811	5/28 (18%)
		PPR repeat	485..514	CDD:276811	5/28 (18%)
		PPR repeat	552..576	CDD:276811	9/77 (12%)
AT3G07290	NP_187385.1	PPR repeat	128..154	CDD:276811
		PPR repeat	160..189	CDD:276811
		PPR repeat	198..224	CDD:276811
		PPR_2	234..277	CDD:372443	3/10 (30%)
		PPR repeat	234..259	CDD:276811
		PLN03218	<264..>627	CDD:215636	90/392 (23%)
		PPR repeat	268..295	CDD:276811	7/28 (25%)
		PPR repeat	301..330	CDD:276811	9/28 (32%)
		PPR repeat	336..365	CDD:276811	9/38 (24%)
		PPR repeat	371..400	CDD:276811	11/28 (39%)
		PPR repeat	406..435	CDD:276811	9/31 (29%)
		PPR repeat	441..467	CDD:276811	5/29 (17%)
		PPR repeat	476..505	CDD:276811	2/28 (7%)
		PPR repeat	511..540	CDD:276811	8/41 (20%)
		PPR repeat	548..575	CDD:276811	3/26 (12%)
		PPR repeat	583..610	CDD:276811	3/26 (12%)
		PPR_2	614..663	CDD:372443	12/48 (25%)
		PPR repeat	616..645	CDD:276811	5/28 (18%)
		PPR_2	649..696	CDD:372443	15/51 (29%)
		PPR repeat	651..680	CDD:276811	8/28 (29%)
		PPR repeat	745..768	CDD:276811	3/22 (14%)
		PPR repeat	774..802	CDD:276811	4/27 (15%)
		PPR repeat	808..837	CDD:276811	9/35 (26%)
		PPR repeat	846..875	CDD:276811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960