DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT2G37230

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_181260.1	Gene:	AT2G37230 / 818300	AraportID:	AT2G37230	Length:	757	Species:	Arabidopsis thaliana

Alignment Length:	697	Identity:	134/697 - (19%)
Similarity:	247/697 - (35%)	Gaps:	198/697 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRLISRSMSCHIRGLQLNATGRRLNSYNISRLVILPATWSCSQNRLLHVRITDQQAGLETKREAN 67
            :..||||.....:.....:..|..|    |.|..||..:|..:               ||:..||
plant     1 MAFISRSKRYQSKARVYLSLPRSSN----SSLFSLPRLFSTIE---------------ETQTPAN 46

  Fly    68 RN---QNPFREEVFEELITAAPKE--HQKFKPEKKPKEKSTKKVQD----FGDPDTFGDAKVAAT 123
            .|   |:|..:...::.:|:....  .::|   ::.|.::.:|::|    ..|...:......:.
plant    47 ANPETQSPDAKSETKKNLTSTETRPLRERF---QRGKRQNHEKLEDTICRMMDNRAWTTRLQNSI 108

  Fly   124 EDPGDVEEEEFLSNSTRRSKKLK-AVEYARQIK----------DHLK-------ANRLNEAIAVL 170
            .|.....:...:.|....:|||: |:::.|..:          .|:|       .::||.|..:|
plant   109 RDLVPEWDHSLVYNVLHGAKKLEHALQFFRWTERSGLIRHDRDTHMKMIKMLGEVSKLNHARCIL 173

  Fly   171 EQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGGTYTSLFNACANAPSV 235
            ..  :.|.....|:.::.:||....|||..:::..::.||:..|::.|..:|.|||..
plant   174 LD--MPEKGVPWDEDMFVVLIESYGKAGIVQESVKIFQKMKDLGVERTIKSYNSLFKV------- 229

  Fly   236 SDGLAKAQILR-----------ENMLEKGYEPNVKNYNAMIKAYGRCGDVDTAYMLADEMMERQL 289
                    |||           ..|:.:|.||....||.|:..:                   .|
plant   230 --------ILRRGRYMMAKRYFNKMVSEGVEPTRHTYNLMLWGF-------------------FL 267

  Fly   290 ELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLRCARDCGFGDLDSMREV 354
            .|..:|                  ||..:.:|..||||||..:||.|:.  ..|.|..:|...::
plant   268 SLRLET------------------ALRFFEDMKTRGISPDDATFNTMIN--GFCRFKKMDEAEKL 312

  Fly   355 IDKIAPSAARKKPVLQLEKGQQDDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPHLGSLVA 419
            ..::              ||.:.. |||.:.||.:...:.|......|.:
plant   313 FVEM--------------KGNKIG-PSVVSYTTMIKGYLAVDRVDDGLRI--------------- 347

  Fly   420 LEEVTRPHERFLLLGGLTGFLEHMKQHNITPDIETFTAML-------EVIPPTNAAEKQLLTFVR 477
                                .|.|:...|.|:..|::.:|       :::...|..:..:   .:
plant   348 --------------------FEEMRSSGIEPNATTYSTLLPGLCDAGKMVEAKNILKNMM---AK 389

  Fly   478 KIGLKADIDFFNILIKKRSMRFDYESAKEVLLMIRTAGLRPDIVTYGVLALG-CRTQ--EEAREL 539
            .|..|.:..|..:|: .:|...|..:|.|||..:.|..:..:...||||... |:..  ..|.:|
plant   390 HIAPKDNSIFLKLLV-SQSKAGDMAAATEVLKAMATLNVPAEAGHYGVLIENQCKASAYNRAIKL 453

  Fly   540 LEQM--------HVAGIKMNMPILGAMLRQGCANKSFSYVNEIIQLSLEEGLKPNEAFLRHLHNF 596
            |:.:        |...::|.......::...|.|...:....:.:..::.|::..:|    |:|.
plant   454 LDTLIEKEIILRHQDTLEMEPSAYNPIIEYLCNNGQTAKAEVLFRQLMKRGVQDQDA----LNNL 514

  Fly   597 HRGCARA--IDARHPSTKTAAFKKGHSKFCDKYRLY---YEEQGLSG 638
            .||.|:.  .|:.:...|..: ::|..:..:.|.|.   |..:|..|
plant   515 IRGHAKEGNPDSSYEILKIMS-RRGVPRESNAYELLIKSYMSKGEPG 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	10/45 (22%)
		PPR_2	182..231	CDD:289786	14/48 (29%)
		PPR	185..215	CDD:279828	7/29 (24%)
		PPR repeat	186..213	CDD:276811	7/26 (27%)
		PPR repeat	219..252	CDD:276811	8/43 (19%)
		PPR_1	252..284	CDD:289614	6/31 (19%)
		PPR_2	256..304	CDD:289786	7/47 (15%)
		PPR repeat	258..287	CDD:276811	3/28 (11%)
		PPR repeat	293..324	CDD:276811	4/30 (13%)
		PPR repeat	330..357	CDD:276811	6/26 (23%)
		PPR repeat	485..514	CDD:276811	8/28 (29%)
		PPR repeat	552..576	CDD:276811	2/23 (9%)
AT2G37230	NP_181260.1	PPR repeat	120..143	CDD:276811	6/22 (27%)
		PPR repeat	152..179	CDD:276811	6/28 (21%)
		PPR repeat	187..214	CDD:276811	7/26 (27%)
		PPR_2	190..228	CDD:289786	12/37 (32%)
		PPR_2	222..265	CDD:289786	14/57 (25%)
		PPR	222..254	CDD:273253	10/46 (22%)
		PPR repeat	222..249	CDD:276811	8/41 (20%)
		PPR_2	253..302	CDD:289786	19/87 (22%)
		PPR	256..290	CDD:273253	14/70 (20%)
		PPR repeat	257..284	CDD:276811	9/63 (14%)
		PPR_1	284..317	CDD:289614	12/48 (25%)
		PPR_2	288..335	CDD:289786	15/63 (24%)
		PPR repeat	292..319	CDD:276811	7/42 (17%)
		PPR_2	323..372	CDD:289786	13/83 (16%)
		PPR repeat	325..354	CDD:276811	7/63 (11%)
		PPR	326..360	CDD:273253	8/68 (12%)
		PPR_1	355..386	CDD:289614	5/30 (17%)
		PPR repeat	360..389	CDD:276811	3/31 (10%)
		PPR repeat	396..422	CDD:276811	8/26 (31%)
		PPR repeat	476..503	CDD:276811	2/26 (8%)
		PPR repeat	508..537	CDD:276811	8/33 (24%)
		PPR repeat	543..572	CDD:276811	5/18 (28%)
		PPR repeat	578..607	CDD:276811
		PPR repeat	652..676	CDD:276811
		PPR repeat	682..711	CDD:276811
		PPR repeat	717..745	CDD:276811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000