DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT2G35130

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_001189682.1	Gene:	AT2G35130 / 818079	AraportID:	AT2G35130	Length:	613	Species:	Arabidopsis thaliana

Alignment Length:	560	Identity:	129/560 - (23%)
Similarity:	207/560 - (36%)	Gaps:	152/560 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LPAT---WSCSQNRLLHVRITDQQAGLETKREANRNQNPFREEV--FEELITAAPKEHQKFKPEK 96
            ||:|   |....|..:.:|:..:...:....|....::.|:.:|  |..||.|   ..|||
plant   134 LPSTHASWDDLINVSVQLRLNKKWDSIILVCEWILRKSSFQPDVICFNLLIDA---YGQKF---- 191

  Fly    97 KPKEKSTKKVQDFGDPDTFGDAKVAATED-----------PGDVEEEEF----LSNSTRRSKKLK 146
            :.||..:..||       ..:::...|||           .|.:|..|.    :.|.....|.:.
plant   192 QYKEAESLYVQ-------LLESRYVPTEDTYALLIKAYCMAGLIERAEVVLVEMQNHHVSPKTIG 249

  Fly   147 AVEYARQIKDHLK-ANRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKM 210
            ...|...|:..:| .....|||.|. ||| |.||.||....|||:|:...||..:..::.||.:|
plant   250 VTVYNAYIEGLMKRKGNTEEAIDVF-QRM-KRDRCKPTTETYNLMINLYGKASKSYMSWKLYCEM 312

  Fly   211 RQRGLQVTGGTYTSLFNACANAPSVSDGLA-KAQILRENMLEKGYEPNVKNYNAMIKAYGRCGDV 274
            |....:....|||:|.||.|.     :||. ||:.:.|.:.|.|.||:|..|||::::|.|.|..
plant   313 RSHQCKPNICTYTALVNAFAR-----EGLCEKAEEIFEQLQEDGLEPDVYVYNALMESYSRAGYP 372

  Fly   275 DTAYMLADEMMERQLELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLRC 339
            ..|..:...|.....|.:..::|.::.|......|....|:  :..|.:.||:|...|...:|..
plant   373 YGAAEIFSLMQHMGCEPDRASYNIMVDAYGRAGLHSDAEAV--FEEMKRLGIAPTMKSHMLLLSA 435

  Fly   340 ---ARDCGFGD-----------------LDSMREVIDKIAPSAARKKPVLQLEKGQQDDLPSVEA 384
               |||....:                 |:||..:..::......:|.:.::|.|
plant   436 YSKARDVTKCEAIVKEMSENGVEPDTFVLNSMLNLYGRLGQFTKMEKILAEMENG---------- 490

  Fly   385 NTTTLPAQIEVATTASELELPNLLLPQPHLGSLVALEEVTRPHERFLLLGGLTGFLE-------H 442
                 |...:::|.       |:|:.                      :.|..||||       .
plant   491 -----PCTADISTY-------NILIN----------------------IYGKAGFLERIEELFVE 521

  Fly   443 MKQHNITPDIETFTAMLEVIPPTNAAEKQLLTFVRKIGLKADIDFFNILIKKRSMRFDYESAKEV 507
            :|:.|..||:.|:|:.:...     :.|:|                            |....||
plant   522 LKEKNFRPDVVTWTSRIGAY-----SRKKL----------------------------YVKCLEV 553

  Fly   508 LLMIRTAGLRPDIVTYGVLALGCRTQEEARE---LLEQMH 544
            ...:..:|..||..|..||...|.::|:..:   :|..||
plant   554 FEEMIDSGCAPDGGTAKVLLSACSSEEQVEQVTSVLRTMH 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	17/39 (44%)
		PPR_2	182..231	CDD:289786	17/48 (35%)
		PPR	185..215	CDD:279828	10/29 (34%)
		PPR repeat	186..213	CDD:276811	10/26 (38%)
		PPR repeat	219..252	CDD:276811	12/33 (36%)
		PPR_1	252..284	CDD:289614	11/31 (35%)
		PPR_2	256..304	CDD:289786	13/47 (28%)
		PPR repeat	258..287	CDD:276811	9/28 (32%)
		PPR repeat	293..324	CDD:276811	5/30 (17%)
		PPR repeat	330..357	CDD:276811	8/46 (17%)
		PPR repeat	485..514	CDD:276811	3/28 (11%)
		PPR repeat	552..576	CDD:276811
AT2G35130	NP_001189682.1	PPR_2	175..223	CDD:289786	15/61 (25%)
		PPR repeat	179..206	CDD:276811	11/40 (28%)
		PPR_1	209..239	CDD:289614	6/29 (21%)
		PPR repeat	212..241	CDD:276811	5/28 (18%)
		PPR_2	250..298	CDD:289786	19/49 (39%)
		PPR	252..286	CDD:273253	15/35 (43%)
		PPR repeat	252..280	CDD:276811	11/29 (38%)
		PPR_2	284..333	CDD:289786	17/48 (35%)
		PPR	288..321	CDD:273253	10/32 (31%)
		PPR repeat	288..315	CDD:276811	10/26 (38%)
		PPR_2	319..368	CDD:289786	21/53 (40%)
		PPR	322..356	CDD:273253	16/38 (42%)
		PPR repeat	323..350	CDD:276811	12/31 (39%)
		PPR_2	354..403	CDD:289786	13/48 (27%)
		PPR repeat	356..385	CDD:276811	9/28 (32%)
		PPR	357..390	CDD:273253	9/32 (28%)
		PPR_1	385..418	CDD:289614	5/34 (15%)
		PPR_2	389..438	CDD:289786	10/50 (20%)
		PPR repeat	391..419	CDD:276811	5/29 (17%)
		PPR repeat	426..455	CDD:276811	5/28 (18%)
		PPR	432..461	CDD:273253	4/28 (14%)
		PPR_2	459..504	CDD:289786	10/66 (15%)
		PPR repeat	463..490	CDD:276811	5/26 (19%)
		PPR_2	495..543	CDD:289786	14/81 (17%)
		PPR repeat	496..525	CDD:276811	9/57 (16%)
		PPR	497..527	CDD:279828	9/58 (16%)
		PPR_2	529..576	CDD:289786	15/79 (19%)
		PPR repeat	531..560	CDD:276811	7/61 (11%)
		PPR	532..565	CDD:273253	8/65 (12%)
		PPR repeat	566..594	CDD:276811	8/28 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960