DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT2G32630

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_180822.1	Gene:	AT2G32630 / 817823	AraportID:	AT2G32630	Length:	624	Species:	Arabidopsis thaliana

Alignment Length:	654	Identity:	132/654 - (20%)
Similarity:	246/654 - (37%)	Gaps:	176/654 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LNSYNISRLVI----LPATWSCSQ-NRLLHVRITDQQAGLETKREANRNQNPFREEVFEELITAA 85
            ||| |::|||:    || |.||.. .:||              ||...|..|       :|....
plant    60 LNS-NVTRLVLSEPTLP-TQSCIDFFKLL--------------REFESNLKP-------DLTAVV 101

  Fly    86 PKEHQKFKPE------------------KKPKEK----------STKKVQDFGDPDTFGDAKVAA 122
            ...|:.:...                  |:|.|:          |.:|.:.|   :.|.|.....
plant   102 TLSHRLYSNRRFNEMRSLLNSVVNDGFYKRPVEELGSAMVDCDISEEKFEFF---EKFFDLVFRV 163

  Fly   123 TEDPGDVEE---------EEFLSNSTR-------RSKKLKAVE-----YARQIKDHLKANRLNEA 166
            ..|.|..||         ::.||...|       .:||.:.::     :.|.:...:|....:..
plant   164 YVDNGMFEEGLRVFDYMVKKGLSIDERSCIVFLVAAKKRRRIDLCLEIFRRMVDSGVKITVYSLT 228

  Fly   167 IAV----------LEQRMLKE---DRAKPDKYIYNLLISGCAKAGYTRKAFF-----LYTKMRQR 213
            |.|          ..::::||   ...||:.|.||.:|:     .|.::..|     :...|::.
plant   229 IVVEGLCRRGEVEKSKKLIKEFSVKGIKPEAYTYNTIIN-----AYVKQRDFSGVEGVLKVMKKD 288

  Fly   214 GLQVTGGTYTSLFNACANAPSVSDG-LAKAQILRENMLEKGYEPNVKNYNAMIKAYGRCGDVDTA 277
            |:.....|||.|...     ||.:| ::.|:.|.:.|.|:|.|.:|..|.::|....|.|::..|
plant   289 GVVYNKVTYTLLMEL-----SVKNGKMSDAEKLFDEMRERGIESDVHVYTSLISWNCRKGNMKRA 348

  Fly   278 YMLADEMMERQLELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLRCARD 342
            ::|.||:.|:.|..::.|:..|:.......|.|....|:  :.|..:|::.....||.::    |
plant   349 FLLFDELTEKGLSPSSYTYGALIDGVCKVGEMGAAEILM--NEMQSKGVNITQVVFNTLI----D 407

  Fly   343 --CGFGDLDSMREVIDKIAPSAARKKPVLQLEKGQQDDLPSVEANTTTLPAQIEVATTASELELP 405
              |..|.:|....:.|           |:: :||.|.|:  ...||        :|:..:.|:
plant   408 GYCRKGMVDEASMIYD-----------VME-QKGFQADV--FTCNT--------IASCFNRLK-- 448

  Fly   406 NLLLPQPHLGSLVALEEVTRPHERFLLLGGLTGFLEHMKQHNITPDIETFTAMLEVIPPTNAAE- 469
                         ..:|..:             :|..|.:..:.....::|.:::|.......|
plant   449 -------------RYDEAKQ-------------WLFRMMEGGVKLSTVSYTNLIDVYCKEGNVEE 487

  Fly   470 -KQLLTFVRKIGLKADIDFFNILIKKRSMRFDYESAKEVLLMIRTAGLRPDIVTYGVLALG-CRT 532
             |:|...:...|::.:...:|::|.....:...:.|:::...:...|:.||..||..|..| |..
plant   488 AKRLFVEMSSKGVQPNAITYNVMIYAYCKQGKIKEARKLRANMEANGMDPDSYTYTSLIHGECIA 552

  Fly   533 Q--EEARELLEQMHVAGIKMN----MPILGAMLRQGCANKSFSYVNEIIQLSLEEGLKPNEAFLR 591
            .  :||..|..:|.:.|:..|    ..::..:.:.|.::::|...:|:.:.......|...|.:.
plant   553 DNVDEAMRLFSEMGLKGLDQNSVTYTVMISGLSKAGKSDEAFGLYDEMKRKGYTIDNKVYTALIG 617

  Fly   592 HLHN 595
            .:|:
plant   618 SMHS 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	11/51 (22%)
		PPR_2	182..231	CDD:289786	13/53 (25%)
		PPR	185..215	CDD:279828	7/34 (21%)
		PPR repeat	186..213	CDD:276811	6/31 (19%)
		PPR repeat	219..252	CDD:276811	10/33 (30%)
		PPR_1	252..284	CDD:289614	10/31 (32%)
		PPR_2	256..304	CDD:289786	13/47 (28%)
		PPR repeat	258..287	CDD:276811	9/28 (32%)
		PPR repeat	293..324	CDD:276811	6/30 (20%)
		PPR repeat	330..357	CDD:276811	6/28 (21%)
		PPR repeat	485..514	CDD:276811	3/28 (11%)
		PPR repeat	552..576	CDD:276811	3/23 (13%)
AT2G32630	NP_180822.1	PPR_2	<201..236	CDD:289786	5/34 (15%)
		PPR_2	223..271	CDD:289786	11/52 (21%)
		PPR repeat	226..253	CDD:276811	4/26 (15%)
		PPR	260..293	CDD:273253	8/37 (22%)
		PPR repeat	261..288	CDD:276811	6/31 (19%)
		PPR repeat	294..323	CDD:276811	10/33 (30%)
		PPR_2	295..341	CDD:289786	16/50 (32%)
		PPR	295..325	CDD:279828	11/34 (32%)
		PPR_1	323..354	CDD:289614	9/30 (30%)
		PPR_2	328..376	CDD:289786	13/47 (28%)
		PPR repeat	329..358	CDD:276811	9/28 (32%)
		PPR_1	358..391	CDD:289614	6/34 (18%)
		PPR_2	362..411	CDD:289786	10/54 (19%)
		PPR repeat	364..393	CDD:276811	6/30 (20%)
		PPR_1	393..426	CDD:289614	9/47 (19%)
		PPR_2	400..444	CDD:289786	15/69 (22%)
		PPR repeat	401..428	CDD:276811	8/42 (19%)
		PPR repeat	434..463	CDD:276811	7/66 (11%)
		PPR	435..469	CDD:273253	7/69 (10%)
		PPR_1	464..496	CDD:289614	5/31 (16%)
		PPR_2	468..516	CDD:289786	8/47 (17%)
		PPR repeat	471..498	CDD:276811	5/26 (19%)
		PPR_1	498..531	CDD:289614	4/32 (13%)
		PPR_2	502..550	CDD:289786	10/47 (21%)
		PPR repeat	504..533	CDD:276811	3/28 (11%)
		PPR_1	533..565	CDD:289614	11/31 (35%)
		PPR_2	537..586	CDD:289786	13/48 (27%)
		PPR repeat	539..565	CDD:276811	8/25 (32%)
		PPR_2	573..616	CDD:289786	6/42 (14%)
		PPR repeat	574..603	CDD:276811	3/28 (11%)
		PPR	575..604	CDD:279828	3/28 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	1	1.010	-	-		QHG54853
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.060