DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT2G26790

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_001318293.1	Gene:	AT2G26790 / 817220	AraportID:	AT2G26790	Length:	799	Species:	Arabidopsis thaliana

Alignment Length:	543	Identity:	109/543 - (20%)
Similarity:	195/543 - (35%)	Gaps:	150/543 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 FLSNSTRRSKKLKAVEYARQIKDHLKANRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAG 198
            ||.....:..|:..|..:..::.:.|.:...||:...::  .::.....|:..||:.....:|.|
plant   340 FLDKMLGKGLKVNCVIVSLILQCYCKMDMCLEALEKFKE--FRDMNIFLDRVCYNVAFDALSKLG 402

  Fly   199 YTRKAFFLYTKMRQRGLQVTGGTYTSLFNACANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNA 263
            ...:||.|..:|:.||:......||:|.:.......|.|.|.    |.:.|:..|..|::..||.
plant   403 RVEEAFELLQEMKDRGIVPDVINYTTLIDGYCLQGKVVDALD----LIDEMIGNGMSPDLITYNV 463

  Fly   264 MIKAYGRCGDVDTAYMLADEM--------------------MERQLELNADTFNFLLQACASNSE 308
            ::....|.|..:....:.:.|                    ..|:::...|.|:.|.|.|..|..
plant   464 LVSGLARNGHEEEVLEIYERMKAEGPKPNAVTNSVIIEGLCFARKVKEAEDFFSSLEQKCPENKA 528

  Fly   309 ---HGFRHALLTWHNMLQRGISPDYYSFNAMLRCARD-------------CGFGDLDSMREVIDK 357
               .|:..|          |:|...|  .|.:|....             |..|.|:...:|:.|
plant   529 SFVKGYCEA----------GLSKKAY--KAFVRLEYPLRKSVYIKLFFSLCIEGYLEKAHDVLKK 581

  Fly   358 IAPSAARKKPVLQLEKGQQDDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPHLGSLVALEE 422
            :  ||.|.:|      |:.                                :....:|:...|..
plant   582 M--SAYRVEP------GRS--------------------------------MCGKMIGAFCKLNN 606

  Fly   423 VTRPHERFLLLGGLTGFLEHMKQHNITPDIETFTAMLEVIPPTNAAEK--QLLTFVRKIGLKADI 485
            |......|          :.|.:..:.||:.|:|.|:......|..:|  .|...:::.|:|.|:
plant   607 VREAQVLF----------DTMVERGLIPDLFTYTIMIHTYCRLNELQKAESLFEDMKQRGIKPDV 661

  Fly   486 DFFNILIKKRSMRFDYE--------------SAKEVLLMIRTAGLRPDIVTYGVLA-LGCRTQ-- 533
            ..:.:|: .|.::.|.|              .|.|||.....||:..|:|.|.||. ..|:..
plant   662 VTYTVLL-DRYLKLDPEHHETCSVQGEVGKRKASEVLREFSAAGIGLDVVCYTVLIDRQCKMNNL 725

  Fly   534 EEARELLEQMHVAGIKMNM----PILGAMLRQGCANKSFSYVNEIIQLSLEEGLKPNEAFLRHLH 594
            |:|.||.::|..:|::.:|    .::.:..|:|..:.:.:.|.|   ||.:..: |:|:|
plant   726 EQAAELFDRMIDSGLEPDMVAYTTLISSYFRKGYIDMAVTLVTE---LSKKYNI-PSESF----- 781

  Fly   595 NFHRGCARAIDARHPSTKTAAFK 617
                         ..:.|:||.|
plant   782 -------------EAAVKSAALK 791

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	6/38 (16%)
		PPR_2	182..231	CDD:289786	14/48 (29%)
		PPR	185..215	CDD:279828	9/29 (31%)
		PPR repeat	186..213	CDD:276811	8/26 (31%)
		PPR repeat	219..252	CDD:276811	8/32 (25%)
		PPR_1	252..284	CDD:289614	6/31 (19%)
		PPR_2	256..304	CDD:289786	11/67 (16%)
		PPR repeat	258..287	CDD:276811	5/48 (10%)
		PPR repeat	293..324	CDD:276811	8/33 (24%)
		PPR repeat	330..357	CDD:276811	7/39 (18%)
		PPR repeat	485..514	CDD:276811	8/42 (19%)
		PPR repeat	552..576	CDD:276811	5/27 (19%)
AT2G26790	NP_001318293.1	PPR repeat	151..175	CDD:276811
		PLN03081	153..>521	CDD:215563	37/186 (20%)
		PPR repeat	181..210	CDD:276811
		PPR repeat	245..274	CDD:276811
		PPR repeat	289..312	CDD:276811
		PPR repeat	320..347	CDD:276811	2/6 (33%)
		PPR repeat	355..382	CDD:276811	3/28 (11%)
		PLN03218	<387..>668	CDD:215636	66/346 (19%)
		PPR repeat	390..417	CDD:276811	8/26 (31%)
		PPR repeat	423..452	CDD:276811	8/32 (25%)
		PPR repeat	458..485	CDD:276811	4/26 (15%)
		PPR repeat	493..522	CDD:276811	4/28 (14%)
		PPR repeat	558..585	CDD:276811	6/28 (21%)
		PPR repeat	593..620	CDD:276811	5/36 (14%)
		PPR repeat	626..655	CDD:276811	6/28 (21%)
		PPR_2	708..756	CDD:372443	13/47 (28%)
		PPR_2	742..776	CDD:372443	7/36 (19%)
		PPR repeat	744..773	CDD:276811	7/31 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050