DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4611 and EMB3111

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_178248.2	Gene:	EMB3111 / 814667	AraportID:	AT2G01390	Length:	577	Species:	Arabidopsis thaliana

Alignment Length:	597	Identity:	132/597 - (22%)
Similarity:	224/597 - (37%)	Gaps:	151/597 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 PKEHQKFKPEKKPKEKSTKKVQDFGDPDTFGDAKVAATEDPGDVEEEEFLSNSTRRSKKLKAVEY 150
            |...::|  .:|||   ..|.|...||..:       |.|         :.::.....|....:.
plant    32 PTNSKRF--SQKPK---LVKTQTLPDPSVY-------TRD---------IVSNIYNILKYSNWDS 75

  Fly   151 ARQIKDHLKA-------NRLNEAIAVLEQRMLKEDRA------KPDKYIYNLLISGCAKAGYTRK 202
            |::...||..       ||:.:|...:::..|..:.|      |.|.:.|..::....:||..:.
plant    76 AQEQLPHLGVRWDSHIINRVLKAHPPMQKAWLFFNWAAQIKGFKHDHFTYTTMLDIFGEAGRIQS 140

  Fly   203 AFFLYTKMRQRGLQVTGGTYTSLFNACANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNAMIKA 267
            .:.::..|:::|:.:...|||||.:..:::..| ||   |..|.|.|.:.|.||.|.:|.|.:|.
plant   141 MYSVFHLMKEKGVLIDTVTYTSLIHWVSSSGDV-DG---AMRLWEEMRDNGCEPTVVSYTAYMKM 201

  Fly   268 YGRCGDVDTAYMLADEMMERQLELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYS 332
            ....|.|:.|..:..||:..::..|..|:..|::...:..:  ...||..:..|.:.|:.||..:
plant   202 LFADGRVEEATEVYKEMLRSRVSPNCHTYTVLMEYLVATGK--CEEALDIFFKMQEIGVQPDKAA 264

  Fly   333 FNAMLRCARDCGFGDLDSMREVIDKIAPS-AARKKPVL--QLE----KGQQDDL----------- 379
            .|.::  |:...||:...|..|:..:..: ...:.|:.  .||    .|:.|||
plant   265 CNILI--AKALKFGETSFMTRVLVYMKENGVVLRYPIFVEALETLKAAGESDDLLREVNSHISVE 327

  Fly   380 ----------PSVEANTTTLPAQIEVATTASELELPNLLLPQPHLGSLVALEEVTRPHERFLLLG 434
                      |:.|.|.|.......|.::.       ||:.|    :|||::.:
plant   328 SLCSSDIDETPTAEVNDTKNSDDSRVISSV-------LLMKQ----NLVAVDIL----------- 370

  Fly   435 GLTGFLEHMKQHNITPD-------IET-------------FTAMLEV-IPPTNAAEKQLL-TFVR 477
                 |..|:..||..|       |||             |...||: |....:|...|: .|:|
plant   371 -----LNQMRDRNIKLDSFVVSAIIETNCDRCRTEGASLAFDYSLEMGIHLKKSAYLALIGNFLR 430

  Fly   478 KIGLKADIDFFNILIKKRSMRFDYESAKEVLLMIRTAG-------------LRPD----IVTYGV 525
            ...|...|:....::|.:.....|:.|    ::|...|             |.||    :..|..
plant   431 SNELPKVIEVVKEMVKAQHSLGCYQGA----MLIHRLGFGRRPRLAADVFDLLPDDQKGVAAYTA 491

  Fly   526 LA---LGCRTQEEARELLEQMHVAGIKMNMPILGA--MLRQGCANKSFSYVNEIIQLSLEEGLKP 585
            |.   :...:.|:|.::|.:|....|   ||.||.  :|..| ..|:..:..|:..|..|:  |.
plant   492 LMDVYISAGSPEKAMKILREMREREI---MPSLGTYDVLLSG-LEKTSDFQKEVALLRKEK--KS 550

  Fly   586 NEAFLRHLHNFH 597
            ..|..|...|.|
plant   551 LVASARFRENVH 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	10/51 (20%)
		PPR_2	182..231	CDD:289786	11/48 (23%)
		PPR	185..215	CDD:279828	4/29 (14%)
		PPR repeat	186..213	CDD:276811	4/26 (15%)
		PPR repeat	219..252	CDD:276811	12/32 (38%)
		PPR_1	252..284	CDD:289614	10/31 (32%)
		PPR_2	256..304	CDD:289786	13/47 (28%)
		PPR repeat	258..287	CDD:276811	9/28 (32%)
		PPR repeat	293..324	CDD:276811	5/30 (17%)
		PPR repeat	330..357	CDD:276811	6/26 (23%)
		PPR repeat	485..514	CDD:276811	5/28 (18%)
		PPR repeat	552..576	CDD:276811	8/25 (32%)
EMB3111	NP_178248.2	PPR_2	121..165	CDD:289786	11/43 (26%)
		PPR	123..157	CDD:273253	5/33 (15%)
		PPR repeat	124..151	CDD:276811	4/26 (15%)
		PPR_2	156..202	CDD:289786	19/49 (39%)
		PPR repeat	157..186	CDD:276811	12/32 (38%)
		PPR	158..192	CDD:273253	15/37 (41%)
		PPR_2	190..234	CDD:289786	12/43 (28%)
		PPR repeat	192..221	CDD:276811	9/28 (32%)
		PPR	193..227	CDD:273253	8/33 (24%)
		PPR_2	225..269	CDD:289786	10/45 (22%)
		PPR repeat	227..255	CDD:276811	5/29 (17%)
		PPR	229..258	CDD:279828	5/30 (17%)
		PPR repeat	262..291	CDD:276811	6/30 (20%)
		PPR repeat	420..447	CDD:276811	6/26 (23%)
		PPR_2	484..531	CDD:289786	13/50 (26%)
		PPR repeat	486..515	CDD:276811	6/28 (21%)
		PPR	488..520	CDD:273253	8/34 (24%)
		PPR repeat	521..550	CDD:276811	8/31 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000