DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4611 and AT4G01400

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_001154199.1	Gene:	AT4G01400 / 28719435	AraportID:	AT4G01400	Length:	466	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	99/537 - (18%)
Similarity:	170/537 - (31%)	Gaps:	216/537 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 EHQKFKP-EKKPKEK--STKKVQDFGDPDTFGDAKVAATEDPGDVEEEEFLSNSTRRSKKLKAVE 149
            ||:..|| ...||..  |..:||..          :|:..||...:|               ..:
plant    33 EHEARKPIVSNPKSPIGSPTRVQKL----------IASQSDPLLAKE---------------IFD 72

  Fly   150 YARQIKDHLKANRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRG 214
            ||.| :.:.:.:|.:..|.:     ||..|.:    .:||:..             :..|.|..|
plant    73 YASQ-QPNFRHSRSSHLILI-----LKLGRGR----YFNLIDD-------------VLAKHRSSG 114

  Fly   215 LQVTGGTYTSLFNACANA---------------------PSVSDGLAKAQILRENMLEKGYE--- 255
            ..:||..:|.|....|.|                     |...:.:....:.....|:|.:|
plant   115 YPLTGEIFTYLIKVYAEAKLPEKVLSTFYKMLEFNFTPQPKHLNRILDVLVSHRGYLQKAFELFK 179

  Fly   256 --------PNVKNYNAMIKAYGRCGDVDTAYMLADEMMERQLELNADTFNFLLQA-CASNSEHGF 311
                    ||.::||.:::|:....|:..||.|..:|:||.:..:.|::..|:|. |.....:|
plant   180 SSRLHGVMPNTRSYNLLMQAFCLNDDLSIAYQLFGKMLERDVVPDVDSYKILIQGFCRKGQVNG- 243

  Fly   312 RHALLTWHNMLQRGISPDYYSFNAMLRCARDCGFGDLDSMREVIDKIAPSAARKKPVLQLEKGQQ 376
              |:....:||.:|..||..|:..:|.                      |..||
plant   244 --AMELLDDMLNKGFVPDRLSYTTLLN----------------------SLCRK----------- 273

  Fly   377 DDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPHLGSLVALEEVTRPHERFLLLGGLTGFLE 441
                                                           |:..|.:.||.
plant   274 -----------------------------------------------TQLREAYKLLC------- 284

  Fly   442 HMKQHNITPDIETFTAMLEVIPPTNAAEKQLLTFVRKIGLKADIDFFNILIKKRSMRFDYESAKE 506
            .||.....||:..:..|             :|.|.|               :.|:|     .|::
plant   285 RMKLKGCNPDLVHYNTM-------------ILGFCR---------------EDRAM-----DARK 316

  Fly   507 VLLMIRTAGLRPDIVTYGVLALGCRTQ---EEARELLEQMHVAGIKMNMPILGAMLRQGCANKSF 568
            ||..:.:.|..|:.|:|..|..|...|   :|.::.||:|...|...:..:...:::..|   ||
plant   317 VLDDMLSNGCSPNSVSYRTLIGGLCDQGMFDEGKKYLEEMISKGFSPHFSVSNCLVKGFC---SF 378

  Fly   569 SYVNE---IIQLSLEEG 582
            ..|.|   ::::.::.|
plant   379 GKVEEACDVVEVVMKNG 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	7/38 (18%)
		PPR_2	182..231	CDD:289786	9/48 (19%)
		PPR	185..215	CDD:279828	4/29 (14%)
		PPR repeat	186..213	CDD:276811	4/26 (15%)
		PPR repeat	219..252	CDD:276811	7/53 (13%)
		PPR_1	252..284	CDD:289614	11/42 (26%)
		PPR_2	256..304	CDD:289786	15/48 (31%)
		PPR repeat	258..287	CDD:276811	8/28 (29%)
		PPR repeat	293..324	CDD:276811	8/31 (26%)
		PPR repeat	330..357	CDD:276811	2/26 (8%)
		PPR repeat	485..514	CDD:276811	5/28 (18%)
		PPR repeat	552..576	CDD:276811	5/26 (19%)
AT4G01400	NP_001154199.1	PPR repeat	86..113	CDD:276811	8/48 (17%)
		PPR repeat	119..147	CDD:276811	5/27 (19%)
		PPR_2	158..201	CDD:289786	8/42 (19%)
		PPR repeat	158..184	CDD:276811	3/25 (12%)
		PPR_2	188..237	CDD:289786	15/48 (31%)
		PPR	191..225	CDD:273253	10/33 (30%)
		PPR repeat	192..219	CDD:276811	8/26 (31%)
		PPR_1	219..251	CDD:289614	7/34 (21%)
		PPR_2	223..272	CDD:289786	14/73 (19%)
		PPR repeat	227..254	CDD:276811	7/29 (24%)
		PPR_1	254..287	CDD:289614	12/119 (10%)
		PPR repeat	262..289	CDD:276811	11/113 (10%)
		PPR_1	289..321	CDD:289614	11/64 (17%)
		PPR_2	293..342	CDD:289786	17/81 (21%)
		PPR repeat	295..324	CDD:276811	9/61 (15%)
		PPR_1	324..356	CDD:289614	10/31 (32%)
		PPR_2	328..376	CDD:289786	11/47 (23%)
		PPR repeat	330..359	CDD:276811	9/28 (32%)
		PPR repeat	365..389	CDD:276811	5/26 (19%)
		PPR repeat	400..429	CDD:276811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000