DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prpk and STE11

DIOPT Version :9

Sequence 1:	NP_647948.1	Gene:	Prpk / 38600	FlyBaseID:	FBgn0035590	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_013466.1	Gene:	STE11 / 851076	SGDID:	S000004354	Length:	717	Species:	Saccharomyces cerevisiae

Alignment Length:	199	Identity:	40/199 - (20%)
Similarity:	69/199 - (34%)	Gaps:	71/199 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GAEGRLYLG--DFKGEACLIKERFVKK---------------------------------YRHPE 38
            |:.|.:|||  ...||...:|:..:|.                                 ..||:
Yeast   424 GSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPK 488

  Fly    39 LNTQITRQRMKAEAKASGRCLAAGILAPKILHSDLNTH----------KLYMEYFDAAKTAKQF- 92
            .|..|.|:.:.|......       |..::.|.::.|:          .:::||......:...
Yeast   489 TNQNIHRKMVDALQHEMN-------LLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLN 546

  Fly    93 ----IQETVSTQTEDEAKKCLLEFCTRIGEIIGKMHSNHIIHGDLTTSNILINPKGGDYDVILID 153
                .:|::.|           .|..:|...:..:|..:|||.|:..:||||:.||   .|.:.|
Yeast   547 NYGPFEESLIT-----------NFTRQILIGVAYLHKKNIIHRDIKGANILIDIKG---CVKITD 597

  Fly   154 FGLS 157
            ||:|
Yeast   598 FGIS 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prpk	NP_647948.1	PKc_like	3..224	CDD:304357	40/199 (20%)
STE11	NP_013466.1	SAM_Ste11_fungal	20..82	CDD:188933
		Ras_bdg_2	121..224	CDD:405528
		PKc_like	415..712	CDD:419665	40/199 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000