DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CHMP2B and Chmp2b

DIOPT Version :9

Sequence 1:	NP_647947.1	Gene:	CHMP2B / 38599	FlyBaseID:	FBgn0035589	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_081155.1	Gene:	Chmp2b / 68942	MGIID:	1916192	Length:	213	Species:	Mus musculus

Alignment Length:	205	Identity:	104/205 - (50%)
Similarity:	143/205 - (69%)	Gaps:	3/205 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KKPTVKEQQRENDRSLRKATRDIERERRKMEEEERKLELEIRRNAAAGNNDACRILAKQLVEIRK 72
            ||.||.:..:|.:|.||...|.|.|:|..:|::|::|||||::.|..||.:|||:||||||.:||
Mouse     6 KKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACRVLAKQLVHLRK 70

  Fly    73 QKSRTYAAAGKIQSIGYQNKNMGANIALSEAMGTTAKTMGEMNKVMRPEAIGETVRQFQAANMKM 137
            ||:||:|.:.|:.|:..|.|.|.:.:.::.||.||||||..:||.|.|:...:|::.||..||||
Mouse    71 QKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKM 135

  Fly   138 EMTDEMINDTLDDMLNESGDEEESNAVVNKVLDEIGIEISGKMSSIP-ATGSSDFETSGKRT--E 199
            |||:|||||||||:.:.|.|||||..:||:|||||||||||||:..| |..|....::.|.|  :
Mouse   136 EMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAARSLPSASTSKATISD 200

  Fly   200 KDIADQLAKL 209
            ::|..||..|
Mouse   201 EEIERQLKAL 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHMP2B	NP_647947.1	Snf7	18..186	CDD:281366	92/168 (55%)
Chmp2b	NP_081155.1	Snf7	16..185	CDD:397437	92/168 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..199		5/19 (26%)
		MIT-interacting motif	201..211		4/10 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830715
Domainoid	1	1.000	184	1.000	Domainoid score	I3408
eggNOG	1	0.900	-	-		E1_COG5491
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8534
Inparanoid	1	1.050	191	1.000	Inparanoid score	I3866
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53529
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005657
OrthoInspector	1	1.000	-	-		oto94348
orthoMCL	1	0.900	-	-		OOG6_105602
Panther	1	1.100	-	-	LDO	PTHR10476
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3454
SonicParanoid	1	1.000	-	-		X4058
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790