DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CHMP2B and chmp2b

DIOPT Version :9

Sequence 1:	NP_647947.1	Gene:	CHMP2B / 38599	FlyBaseID:	FBgn0035589	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_998866.1	Gene:	chmp2b / 407966	XenbaseID:	XB-GENE-948820	Length:	214	Species:	Xenopus tropicalis

Alignment Length:	206	Identity:	104/206 - (50%)
Similarity:	144/206 - (69%)	Gaps:	4/206 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KKPTVKEQQRENDRSLRKATRDIERERRKMEEEERKLELEIRRNAAAGNNDACRILAKQLVEIRK 72
            ||.||.:..||.::.||...|.|.|:|..:|::|::||:||::.|.|||.||||:||||||::||
Frog     6 KKKTVDDIIREQNKELRGTQRAITRDRAALEKQEKQLEMEIKKMAKAGNKDACRVLAKQLVQLRK 70

  Fly    73 QKSRTYAAAGKIQSIGYQNKNMGANIALSEAMGTTAKTMGEMNKVMRPEAIGETVRQFQAANMKM 137
            ||:||||.:.|:.|:..|.|.|.:.:.::.||.||||||..:||.|.|:...:|::.||..||||
Frog    71 QKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKM 135

  Fly   138 EMTDEMINDTLDDMLNESGDEEESNAVVNKVLDEIGIEISGKMSSIPATGSSDFETSGKR----T 198
            |||:|||||||||:.:.|.|||||..:||:|||||||||||||:..|:.......||..:    :
Frog   136 EMTEEMINDTLDDIFDASDDEEESQDIVNQVLDEIGIEISGKMAKAPSAAKGLPSTSASKSSGIS 200

  Fly   199 EKDIADQLAKL 209
            :::|..||..|
Frog   201 DEEIERQLKAL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHMP2B	NP_647947.1	Snf7	18..186	CDD:281366	93/167 (56%)
chmp2b	NP_998866.1	Snf7	16..185	CDD:367460	93/168 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..203		4/24 (17%)
		MIT-interacting motif	202..212		4/10 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	189	1.000	Domainoid score	I3232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8534
Inparanoid	1	1.050	198	1.000	Inparanoid score	I3682
OMA	1	1.010	-	-		QHG53529
OrthoDB	1	1.010	-	-		D1480977at2759
OrthoFinder	1	1.000	-	-		FOG0005657
OrthoInspector	1	1.000	-	-		oto104560
Panther	1	1.100	-	-	LDO	PTHR10476
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3454
SonicParanoid	1	1.000	-	-		X4058
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110