Protein Alignment Dhrs4 and hdhA

DIOPT Version :10

• Sequence 1: NP_647946.1
• Gene: Dhrs4 / 38598
• FlyBaseID: FBgn0035588
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_416136.1
• Gene: hdhA / 946151
• ECOCYCID: EG10425
• Length: 255
• Species: Escherichia coli
• Alignment Length: 249
• Identity: 77/249 - (30%)
• Similarity: 131/249 - (52%)
• Gaps: 8/249 - (3%)

  Fly    68 RLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNVHGLKCHVSEP 132
            ||.||.|::|.:..|||..||...|..||:||:|.......:..:.|:::|.......:|.::..
E. coli     8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72

  Fly   133 EDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWD--KIFDVNVKSSYLLAKEALPLL 195
            ::...|.:..|||.||::|||:||..    ||....|..:.|  :.:::||.|.:.|::...|.:
E. coli    73 QELSALADFAISKLGKVDILVNNAGG----GGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPEM 133

  Fly   196 RQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAPGVIRTKFSK 260
            .:.....|:.::|:|..:....:.:|:.||.|...|.:..|.||..:.||||.:|||.|.|...|
E. coli   134 EKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALK 198

  Fly   261 ALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITGESI-VAGGGM 313
            ::...| ..:..|...|:.|||..:::|....||.|..|.:::|:.: |:|||:
E. coli   199 SVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGGGV 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhrs4	NP_647946.1	Rossmann-fold NAD(P)(+)-binding proteins	67..317	CDD:473865	77/249 (31%)
hdhA	NP_416136.1	PRK06113	1..255	CDD:135765	77/249 (31%)