Protein Alignment Dhrs4 and yciK

DIOPT Version :10

• Sequence 1: NP_647946.1
• Gene: Dhrs4 / 38598
• FlyBaseID: FBgn0035588
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_415787.1
• Gene: yciK / 945838
• ECOCYCID: EG11759
• Length: 252
• Species: Escherichia coli
• Alignment Length: 254
• Identity: 67/254 - (26%)
• Similarity: 117/254 - (46%)
• Gaps: 28/254 - (11%)

  Fly    69 LAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRK----------LNLNVH 123
            |..::.:||.::||||...|...|..||.|::..|.::.:....:.:.:          |:|
E. coli    10 LNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEETGRQPQWFILDL--- 71

  Fly   124 GLKCHVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKSSYLLA 188
             |.|   ..|:.:||.:.....:.:|:.::.||.....|..:.|.:.:||..:..|||.::::|.
E. coli    72 -LTC---TSENCQQLAQRIAVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDVMQVNVNATFMLT 132

  Fly   189 KEALPLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAPGV 253
            :..||||.:....|:||.||..|.......|||:.||.|..|:.:..| |...:.:||||:.||.
E. coli   133 QALLPLLLKSDAGSLVFTSSSVGRQGRANWGAYAASKFATEGMMQVLA-DEYQQRLRVNCINPGG 196

  Fly   254 IRTKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITGESIVAGGG 312
            .||....:.:..|...          :|.|..::..:..:|:.:|:...||.:..|..|
E. coli   197 TRTAMRASAFPTEDPQ----------KLKTPADIMPLYLWLMGDDSRRKTGMTFDAQPG 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhrs4	NP_647946.1	Rossmann-fold NAD(P)(+)-binding proteins	67..317	CDD:473865	67/254 (26%)
yciK	NP_415787.1	PRK08945	1..246	CDD:236357	67/254 (26%)