Protein Alignment Dhrs4 and OAR1

DIOPT Version :10

• Sequence 1: NP_647946.1
• Gene: Dhrs4 / 38598
• FlyBaseID: FBgn0035588
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_012868.1
• Gene: OAR1 / 853810
• SGDID: S000001538
• Length: 278
• Species: Saccharomyces cerevisiae
• Alignment Length: 274
• Identity: 66/274 - (24%)
• Similarity: 112/274 - (40%)
• Gaps: 51/274 - (18%)

  Fly    73 VAVVTASTDGIGFAIAKRLAEDG-AAVVISSRKQK---------NVDSALAELRKLNLNV----- 122
            ||:||.:|.|||.||.::|.:.| :.:::.|.|:.         .:.|.|:..|:..:.:
Yeast     6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKW 70

  Fly   123 -HGLKCH----VSEPEDR---KQLFEETISKFGK---------LNILVSNAATNPAVGGVLECDE 170
             |.|...    :...:||   ||.:........|         :|:|::.|........|.....
Yeast    71 PHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTAS 135

  Fly   171 KVWDKIFDVNVKS---------SYLLAKEAL--PLLRQQKNSSIVFVSSIAGYDAFELLG--AYS 222
            ::.| |.:||..|         .|::..:..  .|..|....:||.:|||......::.|  .||
Yeast   136 QIQD-IMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYS 199

  Fly   223 VSKTALIGLTKAAAKDLAPEGIRVNCLAPGVIRTKFSKALYENESANEAALSKIPMGRLGTS--E 285
            .||.||...|:..|.::.|..||...::||:::   ...:.:|.......:.:..:|..|||  .
Yeast   200 ASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK---GTDMIQNLPVEAKEMLERTIGASGTSAPA 261

  Fly   286 EMAGVVSFLVSEDA 299
            |:|..|..|.|..|
Yeast   262 EIAEEVWSLYSRTA 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhrs4	NP_647946.1	Rossmann-fold NAD(P)(+)-binding proteins	67..317	CDD:473865	66/274 (24%)
OAR1	NP_012868.1	SDR_c	7..275	CDD:212491	64/271 (24%)