Protein Alignment CG10672 and HSD17B14

DIOPT Version :9

• Sequence 1: NP_647946.1
• Gene: CG10672 / 38598
• FlyBaseID: FBgn0035588
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_057330.2
• Gene: HSD17B14 / 51171
• HGNCID: 23238
• Length: 270
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 88/260 - (33%)
• Similarity: 133/260 - (51%)
• Gaps: 27/260 - (10%)

  Fly    65 TMKRLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNVHG---LK 126
            |..|.||||.|||....|||..|.:.....||.|||..:.:...       |.|...:.|   :.
Human     3 TGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGG-------RALEQELPGAVFIL 60

  Fly   127 CHVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKSSYLLAKEA 191
            |.|::.:|.|.|..|||.:||:|:.:|:||..:|......|...:.:.::.::|:..:|.|.|.|
Human    61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125

  Fly   192 LPLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAPGVIRT 256
            ||.||:.: .:::.:||:.|.........|..:|.|:..:|||.|.|.:|.|:||||::||.|.|
Human   126 LPYLRKSQ-GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWT 189

  Fly   257 KFSKALYENESA---------NEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITG-ESIVAGG 311
                .|:|..:|         .|..|:: |:||:|...|:.....||.|| |.:.|| |.:|.||
Human   190 ----PLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGG 248

  Fly   312  311
            Human   249  248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10672	NP_647946.1	NADB_Rossmann	67..317	CDD:304358	87/258 (34%)
		fabG	67..316	CDD:235975	87/258 (34%)
HSD17B14	NP_057330.2	RDH_SDR_c	1..256	CDD:187638	88/260 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810