DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10672 and dhs-6

DIOPT Version :9

Sequence 1:	NP_647946.1	Gene:	CG10672 / 38598	FlyBaseID:	FBgn0035588	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001021972.1	Gene:	dhs-6 / 3565470	WormBaseID:	WBGene00000970	Length:	418	Species:	Caenorhabditis elegans

Alignment Length:	265	Identity:	67/265 - (25%)
Similarity:	121/265 - (45%)	Gaps:	32/265 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 RLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQK-------NVDSALAELRKLNLNVHGL 125
            :..|:..::|.::.|||..||.:||:|||.:|::::...       .:.||..|:.|  .....|
Worm     6 KFVGRTVLITGASRGIGKEIALKLAKDGANIVVAAKTATAHPKLPGTIYSAAEEIEK--AGGKAL 68

  Fly   126 KCHVSEPEDR--KQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKSSYLLA 188
            .|.|...::.  |...||.:.|||.::||::||:. .::......:.|.:|.:..:|.:.::|:.
Worm    69 PCIVDVRDEASVKASVEEAVKKFGGIDILINNASA-ISLTDTENTEMKRYDLMHSINTRGTFLMT 132

  Fly   189 KEALPLLRQQKNSSIVFVSSIAGYDA--FELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAP 251
            |..||.|:..||..::.:|.....:.  |....||:::|..:........::..|.||.||.|.|
Worm   133 KTCLPYLKSGKNPHVLNISPPLLMETRWFANHVAYTMAKYGMSMCVLGQHEEFRPHGIAVNALWP 197

  Fly   252 GVIRTKFSKALYE--NESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITG-----ESIVA 309
               .|....|..|  ::...||...|..:        ||.....::|:::...||     |.|:.
Worm   198 ---LTAIWTAAMEMLSDKGGEAGSRKPSI--------MADAAYAVLSKNSKDFTGNFCIDEDILK 251

  Fly   310 GGGMT 314
            ..|:|
Worm   252 AEGVT 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10672	NP_647946.1	NADB_Rossmann	67..317	CDD:304358	67/265 (25%)
CG10672	NP_647946.1	fabG	67..316	CDD:235975	67/265 (25%)
dhs-6	NP_001021972.1	PRK08278	9..275	CDD:181349	67/262 (26%)
dhs-6	NP_001021972.1	SCP2	319..411	CDD:376720
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810