DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10672 and hsdl2

DIOPT Version :9

Sequence 1:	NP_647946.1	Gene:	CG10672 / 38598	FlyBaseID:	FBgn0035588	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_955893.1	Gene:	hsdl2 / 322347	ZFINID:	ZDB-GENE-030131-1066	Length:	415	Species:	Danio rerio

Alignment Length:	262	Identity:	69/262 - (26%)
Similarity:	119/262 - (45%)	Gaps:	45/262 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 RLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQK-------NVDSALAELRKLNLNVHGL 125
            :|||....:|.::.|||.|||.:.|:|||.|||:::...       .:.:|.||:..  .....|
Zfish     7 KLAGCTIFITGASRGIGKAIALKAAQDGANVVIAAKTADPHPKLPGTIYTAAAEIEA--AGGKAL 69

  Fly   126 KCHVSEPEDRKQL---FEETISKFGKLNILVSNA-ATNPAVGGVLECDEKVWDKIFDVNVKSSYL 186
            .| :.:..|.||:   .|:.:.|||.::|||:|| |.|  :.|.|:...|..|.:..:|::.:||
Zfish    70 PC-IVDVRDEKQINDAVEQAVEKFGGIDILVNNASAIN--LTGTLQTPMKKADLMLGINLRGTYL 131

  Fly   187 LAKEALPLLRQQKNSSIVFVSSIAGYDA--FELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCL 249
            .:|..:|.|.:.||..|:.:|.....:.  |:...||:::|..:.......|::.. ..|.||.|
Zfish   132 TSKLCIPHLLKSKNPHILNLSPPLNLNPIWFKNHTAYTIAKYGMSMCVLGMAEEFR-GSIAVNAL 195

  Fly   250 APGVIRTKFSKALYENESANEAALSKIPMGRLGTSE--------EMAGVVSFLVSEDAGYITGES 306
            .|                  :.|:....|..||.||        |:....::.:.:.....||:.
Zfish   196 WP------------------KTAIQTAAMDMLGGSEVGKQCRKVEIMADAAYAIFKQPTSFTGQF 242

  Fly   307 IV 308
            ::
Zfish   243 VI 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10672	NP_647946.1	NADB_Rossmann	67..317	CDD:304358	69/262 (26%)
CG10672	NP_647946.1	fabG	67..316	CDD:235975	69/262 (26%)
hsdl2	NP_955893.1	HSDL2_SDR_c	8..248	CDD:187663	69/261 (26%)
		adh_short	12..210	CDD:278532	59/221 (27%)
		SCP2	311..408	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810