Protein Alignment CG10672 and DHRS4L2

DIOPT Version :9

• Sequence 1: NP_647946.1
• Gene: CG10672 / 38598
• FlyBaseID: FBgn0035588
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_932349.2
• Gene: DHRS4L2 / 317749
• HGNCID: 19731
• Length: 232
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 98/197 - (49%)
• Similarity: 128/197 - (64%)
• Gaps: 0/197 - (0%)

  Fly    53 RLSSSSQSSTAGTMKRLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRK 117
            |.|....||.......|..|||:|||||||||||||:|||:|.|.||:|||||:|||.|:|.|:.
Human    14 RKSVRMASSRMTRRDPLTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQG 78

  Fly   118 LNLNVHGLKCHVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVK 182
            ..|:|.|..|||.:.|||::|....:...|.::|||||||.||..|.:::..|:||||..|:|||
Human    79 EGLSVTGTVCHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVK 143

  Fly   183 SSYLLAKEALPLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVN 247
            :..|:.|..:|.:.::...|:|.|||||.:........|:||||||:||....|.:|||..||||
Human   144 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVN 208

  Fly   248 CL 249
            ||
Human   209 CL 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10672	NP_647946.1	NADB_Rossmann	67..317	CDD:304358	94/183 (51%)
		fabG	67..316	CDD:235975	94/183 (51%)
DHRS4L2	NP_932349.2	NADB_Rossmann	24..>210	CDD:304358	92/185 (50%)
		adh_short	33..210	CDD:278532	91/176 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	238	1.000	Domainoid score	I2300
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3114
Isobase	1	0.950	-	0.772507	Normalized mean entropy	S1637
OMA	1	1.010	-	-		QHG57783
OrthoDB	1	1.010	-	-		D1194344at2759
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	1	1.000	-	-		otm40894
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43943
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X181
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.890