DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10672 and Hsdl2

DIOPT Version :9

Sequence 1:	NP_647946.1	Gene:	CG10672 / 38598	FlyBaseID:	FBgn0035588	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001020868.1	Gene:	Hsdl2 / 313200	RGDID:	1305387	Length:	524	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	73/267 - (27%)
Similarity:	117/267 - (43%)	Gaps:	55/267 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 RLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNVH-----GLKC 127
            :|||....:|.::.|||.|||.:.|:|||.:||:::..:.....|..:......:.     .|.|
  Rat     7 KLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQRHPKLLGTIYTAAEEIEAAGGKALPC 71

  Fly   128 HVSEPEDRKQL---FEETISKFGKLNILVSNAA----TNPAVGGVLECDEKVWDKIFDVNVKSSY 185
             |.:..|.:|:   .|:.:.:||.::|||:||:    ||     .||...|..|.:..||.:.:|
  Rat    72 -VVDVRDEQQINSAVEKAVERFGGIDILVNNASAISLTN-----TLETPTKRVDLMMSVNTRGTY 130

  Fly   186 LLAKEALPLLRQQKNSSIVFVSSIAGYDA--FELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNC 248
            |.:|..:|.|::.|.:.|:.:|.....:.  |:...||:::|..:.......|::...| |.||.
  Rat   131 LTSKACIPFLKKSKVAHILNLSPPLNLNPMWFKQHCAYTIAKYGMSMCVLGMAEEFRGE-IAVNA 194

  Fly   249 LAPGVIRTKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFL----VSEDAGY-------- 301
            |.|   ||               |:....|..||.    |||.|..    :..||.|
  Rat   195 LWP---RT---------------AIHTAAMDMLGG----AGVESQCRKVDIIADAAYSIFKRPKS 237

  Fly   302 ITGESIV 308
            .||..|:
  Rat   238 FTGNFII 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10672	NP_647946.1	NADB_Rossmann	67..317	CDD:304358	73/267 (27%)
CG10672	NP_647946.1	fabG	67..316	CDD:235975	73/267 (27%)
Hsdl2	NP_001020868.1	HSDL2_SDR_c	8..248	CDD:187663	73/266 (27%)
		adh_short	12..197	CDD:278532	53/191 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	283..410
		SCP2	424..517	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810