Protein Alignment Dhrs4 and Bdh2

DIOPT Version :10

• Sequence 1: NP_647946.1
• Gene: Dhrs4 / 38598
• FlyBaseID: FBgn0035588
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001099943.1
• Gene: Bdh2 / 295458
• RGDID: 1309898
• Length: 255
• Species: Rattus norvegicus
• Alignment Length: 257
• Identity: 93/257 - (36%)
• Similarity: 149/257 - (57%)
• Gaps: 16/257 - (6%)

  Fly    62 TAG-TMKRLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNVHGL 125
            ||| ||.||.|||.|:||:..|||.|.|...|.:||.|:.:       |...|:|::|. |..|:
  Rat     6 TAGSTMGRLEGKVIVLTAAAQGIGRASALAFAREGAKVIAT-------DINEAKLQELE-NYPGI 62

  Fly   126 KCHVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKSSYLLAKE 190
            :..|.:...::|: ::..|:..|:::|. |.|.....|.:|:|:||.||...::||:|.||:.|.
  Rat    63 QTRVLDVTKKRQI-DQFASEIEKIDVLF-NVAGFVHHGTILDCEEKDWDFSMNLNVRSMYLMIKA 125

  Fly   191 ALPLLRQQKNSSIVFVSSIA-GYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAPGVI 254
            .||.:..||:.:|:.:||:| .....|....||.:|.|:|||||:.|.|...:|||.||:.||.:
  Rat   126 FLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCPGTV 190

  Fly   255 RT----KFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITGESIVAGGG 312
            .|    :..:|..:.:.|.:|.|::...||..::||:|.:..:|.|:::.|:||..:|..||
  Rat   191 DTPSLQERIQARDDPKEALKAFLNRQKTGRFASAEEVALLCVYLASDESAYVTGTPVVIDGG 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhrs4	NP_647946.1	Rossmann-fold NAD(P)(+)-binding proteins	67..317	CDD:473865	88/251 (35%)
Bdh2	NP_001099943.1	DHRS6_like_SDR_c	15..255	CDD:187626	86/248 (35%)