DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10672 and Dhrs4

DIOPT Version :9

Sequence 1:	NP_647946.1	Gene:	CG10672 / 38598	FlyBaseID:	FBgn0035588	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_695227.2	Gene:	Dhrs4 / 266686	RGDID:	708482	Length:	279	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	133/267 - (49%)
Similarity:	186/267 - (69%)	Gaps:	2/267 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 RLSSSSQSSTAGTMKR--LAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAEL 115
            |...|.:.:::|..::  ||.|||:|||||||||.|||:|||||||.||||||||:|||.|:|.|
  Rat    13 RAWKSVRMASSGLTRQNPLANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATL 77

  Fly   116 RKLNLNVHGLKCHVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVN 180
            :...|:|.|:.|||.:.|||::|....:.....::|||||||.||..|.:::..|:||:|:..:|
  Rat    78 QGEGLSVTGVVCHVGKAEDREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSIN 142

  Fly   181 VKSSYLLAKEALPLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIR 245
            |.:|.::.|..:|.:.::...|:|.|||:||:..|..||.|:||||||:||||..|.:|||:.||
  Rat   143 VTASAMMIKAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIR 207

  Fly   246 VNCLAPGVIRTKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITGESIVAG 310
            |||||||:|:|.||..|::.::..|.....:.:.|||..|:..|:||||.||||.||.||::|.|
  Rat   208 VNCLAPGLIKTHFSSVLWKEKAREEMIKETMQIRRLGKPEDCVGIVSFLCSEDASYINGETVVVG 272

  Fly   311 GGMTARL 317
            ||..:||
  Rat   273 GGTPSRL 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10672	NP_647946.1	NADB_Rossmann	67..317	CDD:304358	128/251 (51%)
CG10672	NP_647946.1	fabG	67..316	CDD:235975	128/250 (51%)
Dhrs4	NP_695227.2	CR_SDR_c	24..279	CDD:187641	129/254 (51%)
Dhrs4	NP_695227.2	Microbody targeting signal	277..279		0/1 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	234	1.000	Domainoid score	I2308
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49646
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3111
OMA	1	1.010	-	-		QHG57783
OrthoDB	1	1.010	-	-		D1194344at2759
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	1	1.000	-	-		otm45032
orthoMCL	1	0.900	-	-		OOG6_102796
Panther	1	1.100	-	-	LDO	PTHR43943
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X181
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840