Protein Alignment Dhrs4 and C06E4.3

DIOPT Version :10

• Sequence 1: NP_647946.1
• Gene: Dhrs4 / 38598
• FlyBaseID: FBgn0035588
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_501156.1
• Gene: C06E4.3 / 182326
• WormBaseID: WBGene00015532
• Length: 277
• Species: Caenorhabditis elegans
• Alignment Length: 266
• Identity: 86/266 - (32%)
• Similarity: 140/266 - (52%)
• Gaps: 27/266 - (10%)

  Fly    68 RLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVD---SALAELRKLNLNVHGLKCHV 129
            |.:||||::|.|:.|||.|.|...|::||.|.::.|.::.:.   .||.:....:.|...:...:
 Worm     4 RFSGKVAIITGSSFGIGRATALLFAKEGAKVTVTGRSEERLQGSKQALLDAGISDSNFLIVPADI 68

  Fly   130 SEPEDRKQLFEETISKFGKLNILVSNAATNPA-----VGGVLECDEKVWDKIFDVNVKSSYLLAK 189
            :....:..|..:|:.|||::||||:||..:.|     .|  |:.....::|:..:||:|...:.:
 Worm    69 TTSSGQDALISKTLEKFGQINILVNNAGASIADSQNRAG--LDQGIDTYEKVLKLNVQSVIEMTQ 131

  Fly   190 EALPLLRQQKNSSIVFVSSIAGYDAFELLGA-YSVSKTALIGLTKAAAKDLAPEGIRVNCLAPGV 253
            :..|.|.:.: ..||.|||:|......:... |.::|.||...|::||.||..:|||||.:.|||
 Worm   132 KIRPHLAKTR-GEIVNVSSVAALKFAHVRNPYYPLAKAALDQYTRSAAIDLISQGIRVNTVNPGV 195

  Fly   254 IRTKF-----------SKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAG-YITGES 306
            :.|.|           |:..|:...||::|   ||.|..|..|.:|..::||...|:. ||.|::
 Worm   196 VATGFHESCTGLSTEESQKFYDKVGANKSA---IPCGFSGRPEHIAKAIAFLADRDSSEYIIGQN 257

  Fly   307 IVAGGG 312
            |:|.||
 Worm   258 IIADGG 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhrs4	NP_647946.1	Rossmann-fold NAD(P)(+)-binding proteins	67..317	CDD:473865	86/266 (32%)
C06E4.3	NP_501156.1	Rossmann-fold NAD(P)(+)-binding proteins	5..267	CDD:473865	85/265 (32%)