DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10672 and dhrs-4

DIOPT Version :9

Sequence 1:	NP_647946.1	Gene:	CG10672 / 38598	FlyBaseID:	FBgn0035588	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_506230.1	Gene:	dhrs-4 / 179772	WormBaseID:	WBGene00010063	Length:	260	Species:	Caenorhabditis elegans

Alignment Length:	255	Identity:	119/255 - (46%)
Similarity:	175/255 - (68%)	Gaps:	4/255 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 KRLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNL-NVHGLKCHVS 130
            :|..||||:|||:|.|||.|||:||.::||:|||.||.|||||.|:..|:...| .|.|:..|::
Worm     6 RRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIA 70

  Fly   131 EPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKSSYLLAKEALPLL 195
            ..:|:|:|.:.|:.||||:||||:|...|||.|.:||..::||||:|:||||:.:.:.|...|.:
Worm    71 STDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKLVHPHI 135

  Fly   196 RQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAPGVIRTKFSK 260
            .::...:|:|.:|.:.|.:...:.||.|:||.|:|||:|.|..||.:.||||.:|||||:||.|:
Worm   136 AKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIKTKMSQ 200

  Fly   261 ALYENESANEAALS---KIPMGRLGTSEEMAGVVSFLVSEDAGYITGESIVAGGGMTARL 317
            .|::.....|..|:   :|.:||||..::.||.|::|.|:|:.|||||.|:..||:.|||
Worm   201 VLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYITGEMIIIAGGVQARL 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10672	NP_647946.1	NADB_Rossmann	67..317	CDD:304358	117/253 (46%)
CG10672	NP_647946.1	fabG	67..316	CDD:235975	116/252 (46%)
dhrs-4	NP_506230.1	SDR	9..260	CDD:330230	116/250 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57783
OrthoDB	1	1.010	-	-		D1194344at2759
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102796
Panther	1	1.100	-	-	LDO	PTHR43943
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X181
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.790