Protein Alignment Dhrs4 and dhs-11

DIOPT Version :10

• Sequence 1: NP_647946.1
• Gene: Dhrs4 / 38598
• FlyBaseID: FBgn0035588
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_499346.2
• Gene: dhs-11 / 176485
• WormBaseID: WBGene00000974
• Length: 244
• Species: Caenorhabditis elegans
• Alignment Length: 261
• Identity: 87/261 - (33%)
• Similarity: 140/261 - (53%)
• Gaps: 36/261 - (13%)

  Fly    69 LAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNVHG---LKCHVS 130
            |:.|:|:||....|||.||.|:.|..||.::::..|:     :.||....||..:|   .:..||
 Worm     2 LSSKLAIVTGGGSGIGQAICKKFAASGARLIVADLKK-----SAAEATAGNLPGNGHSAFEIDVS 61

  Fly   131 EPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKS----SYLLAKEA 191
            :||...:| :|.|...|:...::.|.|.......:|:..:..|..:.:||:.|    |.::|:|:
 Worm    62 DPEHVARL-QEFIKSSGESPSVLVNCAGITKDATLLKMSQNQWQDVMNVNLNSVFLMSQMIARES 125

  Fly   192 L----PLLRQQKNSSIVFVSSIAGYDAFELLG-----AYSVSKTALIGLTKAAAKDLAPEGIRVN 247
            :    ||       |||.||||.|     .:|     .|:.:|:.:||.||:||::||.:.||||
 Worm   126 VAAGSPL-------SIVNVSSIVG-----KIGNFGQTNYAATKSGVIGFTKSAARELATKNIRVN 178

  Fly   248 CLAPGVIRTKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITGESIVAGGG 312
            .:.||.|||..::|:  .....:|.:|.:|..|||.:||:|..|.||.|:.:.|:||.::...||
 Worm   179 AVLPGFIRTPMTEAM--PPKVLDAMVSMVPQRRLGETEEIANAVLFLASDMSSYVTGTTLEVTGG 241

  Fly   313 M 313
            :
 Worm   242 L 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhrs4	NP_647946.1	Rossmann-fold NAD(P)(+)-binding proteins	67..317	CDD:473865	87/261 (33%)
dhs-11	NP_499346.2	BKR_SDR_c	5..243	CDD:187594	86/258 (33%)