Protein Alignment Dhrs4 and Dcxr

DIOPT Version :10

• Sequence 1: NP_647946.1
• Gene: Dhrs4 / 38598
• FlyBaseID: FBgn0035588
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_599214.1
• Gene: Dcxr / 171408
• RGDID: 620031
• Length: 244
• Species: Rattus norvegicus
• Alignment Length: 256
• Identity: 78/256 - (30%)
• Similarity: 123/256 - (48%)
• Gaps: 26/256 - (10%)

  Fly    69 LAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNVHGLKCHVSEP- 132
            |||:.|:||.:..|||.:....|...||.||..||.::::||.:.|            |...||
  Rat     5 LAGRRALVTGAGKGIGRSTVLALQAAGAQVVAVSRTREDLDSLVRE------------CPGVEPV 57

  Fly   133 ----EDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVN----VKSSYLLAK 189
                .| .:..|:.:|..|.:::||:|||. ..:...||..::..|..|:||    |:.|.::|:
  Rat    58 CVDLAD-WEATEQALSNVGPVDLLVNNAAV-ATLQPFLEVTKEACDTSFNVNFRAVVQVSQIVAR 120

  Fly   190 EALPLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAPGVI 254
               .::.:....:||.|||.|...|......|..:|.||..|||..|.:|.|..||||.:.|.|:
  Rat   121 ---GMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVV 182

  Fly   255 RTKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITGESIVAGGGMTA 315
            .|...:|.:.:....:..|.:||:|:....|.:...:.||:|..:...||.::...||..|
  Rat   183 MTPMGRANWSDPHKAKVMLDRIPLGKFAEVENVVDTILFLLSNRSSMTTGSALPVDGGFLA 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhrs4	NP_647946.1	Rossmann-fold NAD(P)(+)-binding proteins	67..317	CDD:473865	78/256 (30%)
Dcxr	NP_599214.1	XR_like_SDR_c	1..243	CDD:187609	77/254 (30%)