Protein Alignment Dhrs4 and Hsd17b8

DIOPT Version :10

• Sequence 1: NP_647946.1
• Gene: Dhrs4 / 38598
• FlyBaseID: FBgn0035588
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_038571.2
• Gene: Hsd17b8 / 14979
• MGIID: 95911
• Length: 259
• Species: Mus musculus
• Alignment Length: 259
• Identity: 86/259 - (33%)
• Similarity: 133/259 - (51%)
• Gaps: 20/259 - (7%)

  Fly    68 RLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNVHG-------- 124
            ||...:|:||.:..|||.||:.|||.:||||...     ::|.|.|:.....|...|
Mouse     6 RLRSALALVTGAGSGIGRAISVRLAAEGAAVAAC-----DLDGAAAQDTVRLLGSPGSEDGAPRG 65

  Fly   125 ----LKCHVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKSSY 185
                .:..||:....::|.||..:.|.:...:|.:.|.......:|...|:.||::..||:|.::
Mouse    66 KHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDRVIAVNLKGTF 130

  Fly   186 LLAKEAL-PLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCL 249
            |:.:.|. .|:......||:.:|||.|.........|:.||..:||||:.||::|...|||.|.:
Mouse   131 LVTQAAAQALVSSGGRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIRCNSV 195

  Fly   250 APGVIRTKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITGESIVAGGGM 313
            .||.|.|..::.:  .|...:...:.||:|.:|..|::|.||:||.|||:|||||.|:...||:
Mouse   196 LPGFIATPMTQKM--PEKVKDKVTAMIPLGHMGDPEDVADVVAFLASEDSGYITGASVEVSGGL 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhrs4	NP_647946.1	Rossmann-fold NAD(P)(+)-binding proteins	67..317	CDD:473865	86/259 (33%)
Hsd17b8	NP_038571.2	Rossmann-fold NAD(P)(+)-binding proteins	11..258	CDD:473865	84/254 (33%)