Protein Alignment Gdap1 and GSTT4

DIOPT Version :10

• Sequence 1: NP_647945.1
• Gene: Gdap1 / 38597
• FlyBaseID: FBgn0035587
• Length: 327
• Species: Drosophila melanogaster
• Sequence 2: NP_001345593.1
• Gene: GSTT4 / 25774
• HGNCID: 26930
• Length: 241
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 57/244 - (23%)
• Similarity: 96/244 - (39%)
• Gaps: 48/244 - (19%)

  Fly    41 KVLMVFYEK-KIDFFPYVVDLCNGEQYSNWFLNLNPKGDVPVLQDGALVIPSSTHIINYVESKFR 104
            :.:.:|.:| .|.|....|||..|..:|..::::||...:|.|:||..::..|..|:.|:..|:.
Human    15 RAVYIFSKKHDIQFNFQFVDLLKGHHHSKGYIDINPLRKLPSLKDGKFILSESAAILYYLCRKYS 79

  Fly   105 GDRSLKP--AHNSKEFDQMLIFEQAMARLPVGTLSLGSFIHDDLK-LVPKAPFIGPVRQSCLKNN 166
            ......|  .|.....|:.:.::....:||:..:..       || |:||           :...
Human    80 APSHWCPPDPHARARVDEFVAWQHTAFQLPMKKIVW-------LKLLIPK-----------ITGE 126

  Fly   167 EKVLDLLRHSVDE-----QATKKAALQHKLDI---QLRRHELASSREEFQKVLDAVRHFLLYVEQ 223
            |...:.:.|:|:|     |..::..||.|:.|   |:...:|.:..|..|.:......||
Human   127 EVSAEKMEHAVEEVKNSLQLFEEYFLQDKMFITGNQISLADLVAVVEMMQPMAANYNVFL----- 186

  Fly   224 ELTAQAPRVEWLTGDELSVADISLGLLLH---RLYQLGFENQFWTFGKL 269
               ..:...||....||::..   ||...   ||.||.    .|.|..|
Human   187 ---NSSKLAEWRMQVELNIGS---GLFREAHDRLMQLA----DWDFSTL 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdap1	NP_647945.1	GstA	30..297	CDD:440390	57/244 (23%)
		GST_C_family	178..285	CDD:470672	25/103 (24%)
GSTT4	NP_001345593.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..78	CDD:469754	18/62 (29%)
		GST_C_Theta	91..217	CDD:198292	31/154 (20%)