Protein Alignment Gdap1 and Gdap1

DIOPT Version :10

• Sequence 1: NP_647945.1
• Gene: Gdap1 / 38597
• FlyBaseID: FBgn0035587
• Length: 327
• Species: Drosophila melanogaster
• Sequence 2: NP_034397.1
• Gene: Gdap1 / 14545
• MGIID: 1338002
• Length: 358
• Species: Mus musculus
• Alignment Length: 323
• Identity: 92/323 - (28%)
• Similarity: 151/323 - (46%)
• Gaps: 26/323 - (8%)

  Fly    24 PANKPV---LFFHPYNFHAQKVLMVFYEKKIDFFPYVVDLCNGEQYSNWFLNLNPKGDVPVLQDG 85
            |.:|.|   |:...::|.:|||.:|..||.:....:.|.|...|....||:.||..|:||||..|
Mouse    19 PPDKEVHLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSAGEVPVLVHG 83

  Fly    86 ALVIPSSTHIINYVESKFRGDRS--LKPAHNSKEFDQMLIFEQAMARLPVGTLSLGSFIHDDLKL 148
            ..:|..:|.||:|:|..|..:|:  |.|...|..:.::..:.:.:..||:...:.|..:|.:|.:
Mouse    84 ENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTV 148

  Fly   149 VPKAPFIGPVR-QSCLKNNEKVLDLLRHSVDEQATKKAALQHKLDIQLRRHE----LASSREEFQ 208
            ....|.....| :|.:.|.|..|..|.....:......|.|.:|..:|..|:    |....:|.:
Mouse   149 DSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELE 213

  Fly   209 KVLDAVRHFLLYVEQELTAQAPRVEWLTGDELSVADISLGLLLHRLYQLGFENQFWTFGKLPQVE 273
            ||||.|...|....:| |.:.....||.|:..::||:||.:.||||..|||..:.|..||.|.:|
Mouse   214 KVLDQVETELQRRNEE-TPEEGNQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGHGKRPNLE 277

  Fly   274 AYFLRFRQRESFHR------------LQPSNFAILREMWTRTPGN---YKLGAGAGFLGMAMF 321
            .|:.|..:|::|::            :.|:.|.:.::...:..|:   ..|..|.|:....:|
Mouse   278 TYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGSTLVVGLLVGMGYFAFMLF 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdap1	NP_647945.1	GstA	30..297	CDD:440390	84/285 (29%)
		GST_C_family	178..285	CDD:470672	37/110 (34%)
Gdap1	NP_034397.1	GST_N_GDAP1	26..98	CDD:239350	26/71 (37%)
		GST_C_GDAP1	179..289	CDD:198336	39/125 (31%)
		Required for mitochondrial localization. /evidence=ECO:0000250	320..358