Protein Alignment Fitm and FITM1

DIOPT Version :9

• Sequence 1: NP_729053.2
• Gene: Fitm / 38596
• FlyBaseID: FBgn0035586
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_981947.1
• Gene: FITM1 / 161247
• HGNCID: 33714
• Length: 292
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 86/325 - (26%)
• Similarity: 136/325 - (41%)
• Gaps: 69/325 - (21%)

  Fly    89 GPDITRSEARGTRPTAAPTSIREILVMGVIHLCKKTIFFNTDLKVALYLGS----------LFVI 143
            ||.:......|.|..|....:.::|    :.:....::|.:: :.|..|||          |..:
Human     4 GPVVGAGLGAGARIQALLGCLLKVL----LWVASALLYFGSE-QAARLLGSPCLRRLYHAWLAAV 63

  Fly   144 SVIGDFVPF---PKTYFARSDNLFNQYFVKIGWGWTLLFVVPFLVLSAYTITCGDHKR--MLRHH 203
            .:.|..:.|   |:|.||...|.||..||...||||..|:..|::|..:..|    :|  :...|
Human    64 VIFGPLLQFHVNPRTIFASHGNFFNIKFVNSAWGWTCTFLGGFVLLVVFLAT----RRVAVTARH 124

  Fly   204 FPRIVIATFFWFFWTKLFNVVENSYGRC---TTKG-----YATKSSCLKAGHLWKGFDISGHAFI 260
            ..|:|:....|....:.|.::|:..|.|   ..:|     ...:.|||.|||.|:|:.:|.|.|:
Human   125 LSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLPQGLLLHELPDRRSCLAAGHQWRGYTVSSHTFL 189

  Fly   261 LIHSSLVLIEEARPIIRWETIKEHIRNERHNRSTAENSGTNPLRTLNEEQMRSLQFLYKRLTPII 325
            |....|::.|||....::..         |......     |||         |.||       :
Human   190 LTFCCLLMAEEAAVFAKYLA---------HGLPAGA-----PLR---------LVFL-------L 224

  Fly   326 RTLFIGMAALQLLWDIMLVGTMLYYHRMIEKVISGIIAILTWYFTYRFWYPTPGLLPEAPGNGSF 390
            ..|.:|      ||:.:|:.|::|:|:...||:...:....||.||..||..| ..|.:||:|.|
Human   225 NVLLLG------LWNFLLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQP-WSPGSPGHGLF 282

  Fly   391  390
            Human   283  282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fitm	NP_729053.2	Scs3p	157..371	CDD:287263	60/223 (27%)
FITM1	NP_981947.1	Scs3p	80..264	CDD:287263	60/223 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157879
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3750
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1621925at2759
OrthoFinder	1	1.000	-	-		FOG0001836
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23129
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850