DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fitm and fitm2

DIOPT Version :9

Sequence 1:	NP_729053.2	Gene:	Fitm / 38596	FlyBaseID:	FBgn0035586	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	XP_012826930.2	Gene:	fitm2 / 100036626	XenbaseID:	XB-GENE-950532	Length:	263	Species:	Xenopus tropicalis

Alignment Length:	279	Identity:	84/279 - (30%)
Similarity:	129/279 - (46%)	Gaps:	57/279 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 LKVALYLGSLFVISVIGDFVPFPKTYFARSDNLFNQYFVKIGWGWTLLFVVPFLVLSAYTITCGD 195
            |...:.||.    |::.:..|.|.:|:....|:.|.||||..|||||..::||:.|:.|.:|...
Frog    30 LLACIVLGG----SLLKELSPLPDSYWNNKRNVLNVYFVKFSWGWTLWLLLPFIALTNYKLTRST 90

  Fly   196 HKRMLRHHFPRIVIATFFWFFWTKLFNVVENSYGRC-------TTKGYATKSSCLKAGHLWKGFD 253
            .|.:.|  ...::::|..|:..|.||..:|:..|.|       ..|.:..:..|...|..|.|||
Frog    91 TKVLRR--LSSLLVSTLIWYLCTNLFLYIEDITGSCYESEAMSDPKEHQDRRECRLHGGYWHGFD 153

  Fly   254 ISGHAFILIHSSLVLIEEARPIIRWETIKEHIRNERHNRSTAENSGTNPLRTLNEEQMRSLQFLY 318
            ||||.|:|.:..|:::||.       :|..:||.|||                           :
Frog   154 ISGHCFLLSYCILLILEET-------SIIPNIRFERH---------------------------W 184

  Fly   319 KRLTPIIRTLFIGMAALQLLWDIMLVGTMLYYHRMIEKVISGIIAILTWYFTYRFWY--P-TPGL 380
            .|:.  |...|..::.|.::|..|.:.|.:|:|.:.:|||.....||.||.|||:||  | :|||
Frog   185 HRMA--INAQFAALSILVIIWVWMFLCTAVYFHNIFQKVIGTAFGILAWYITYRWWYLKPISPGL 247

  Fly   381 LPEAPGNGSFSYQREIPTF 399
            .|     .|.|:..:.|.:
Frog   248 PP-----ASASHSGKEPIY 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fitm	NP_729053.2	Scs3p	157..371	CDD:287263	64/220 (29%)
fitm2	XP_012826930.2	Scs3p	50..235	CDD:402051	65/222 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	87	1.000	Domainoid score	I7877
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H35254
Inparanoid	1	1.050	130	1.000	Inparanoid score	I4512
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1621925at2759
OrthoFinder	1	1.000	-	-		FOG0001836
OrthoInspector	1	1.000	-	-		otm47689
Panther	1	1.100	-	-	LDO	PTHR23129
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1295
SonicParanoid	1	1.000	-	-		X5529
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.100