Protein Alignment AlaRS-m and alaS

DIOPT Version :10

• Sequence 1: NP_523932.2
• Gene: AlaRS-m / 38595
• FlyBaseID: FBgn0028962
• Length: 1012
• Species: Drosophila melanogaster
• Sequence 2: NP_417177.1
• Gene: alaS / 947175
• ECOCYCID: EG10034
• Length: 876
• Species: Escherichia coli
• Alignment Length: 1016
• Identity: 298/1016 - (29%)
• Similarity: 460/1016 - (45%)
• Gaps: 198/1016 - (19%)

  Fly    16 EIRKTFLDHFTVNHGHKFVRSSPVVPFCDPTVAFVNAGMNQFKSVFLGTAAAPHKRVVNSQKCVR 80
            |||:.|||.|. :.||:.|.||.:||..|||:.|.||||||||.||||.....:.|...||:|||
E. coli     7 EIRQAFLDFFH-SKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVR 70

  Fly    81 VGGKHNDLSVVGTDGYHHTFFEMLGNWSFGDYFKREACAMALELLRGP--YNIDPGRLYVTYFAG 143
            .|||||||..||....||||||||||:|||||||.:|...|.|||...  :.:...||:||.:..
E. coli    71 AGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYES 135

  Fly   144 DKVLGIPADLECFEIW-RSLGFPASRILPFG-------CADNFWEMGATGPCGPCTEIHIDHRPD 200
            |.        |.:||| :.:|.|..||:..|       .:||||:||.||||||||||..||...
E. coli   136 DD--------EAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDH 192

  Fly   201 L-----GSVEQRAKLVNAGRSDLTELWNLVFIQYNRHADGSISQLPAHHVDTGMGFERLTAVLQN 260
            :     ||.|:..       ....|:||:||:|:||.|||::..||...||||||.||:.||||:
E. coli   193 IWGGPPGSPEEDG-------DRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQH 250

  Fly   261 KSSNYDTDLFTPIFDGIQQAAKTPVYSGSFPDGGNAAVLDTSYRILADHARMVTACLADGMLPDQ 325
            .:||||.|||..:   ||..||..         |...:.:.|.|::|||.|.....:|||::|..
E. coli   251 VNSNYDIDLFRTL---IQAVAKVT---------GATDLSNKSLRVIADHIRSCAFLIADGVMPSN 303

  Fly   326 NQK---LRRVLRKALNISEHVFAHDKLLTQLVPIVVETLGEAYPEMAAKQQAVIDLICHEQEVYK 387
            ..:   |||::|:|:.....:.|.:....:||..:::.:|.|..:: .:|||.::.:...:|
E. coli   304 ENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDL-KRQQAQVEQVLKTEE--- 364

  Fly   388 NLRESSSKAFAEVLMEFPNLDDIDLMECPGFVPAYRELQMQRCKFSNNTIPGDFLYKLTDTYGLT 452
                   :.||..|.....|.|.:|                 .|.|.:|:.|:..::|.||||..
E. coli   365 -------EQFARTLERGLALLDEEL-----------------AKLSGDTLDGETAFRLYDTYGFP 405

  Fly   453 EESFLKLAELENMNCDLERYRAEVSLAKLKAKGNQRETAGGSLCDLATEQRIAEAQAMLTKRLTP 517
            .:....:....|:..|...:.|.:...:.:|    ||.:|..          |:..||:.
E. coli   406 VDLTADVCRERNIKVDEAGFEAAMEEQRRRA----REASGFG----------ADYNAMIR----- 451

  Fly   518 TDNSHKYTYSFDKESDSYQIPPLKTRVLGMLLNDAEVSRTQGSRIQQPFTDLIS------IVTAG 576
            .|::        .|...|....|..:|..:.::...|             |.|:      :|...
E. coli   452 VDSA--------SEFKGYDHLELNGKVTALFVDGKAV-------------DAINAGQEAVVVLDQ 495

  Fly   577 SNFYYESGGQQSDGGKILVSNHQQPDHPHSLDVIGVKHLNDCVVHICKLSSPTDAFQLAIGDEVE 641
            :.||.|||||..|.|::..:|       .|..|...:.....:.||.||:    |..|.:||.|:
E. coli   496 TPFYAESGGQVGDKGELKGAN-------FSFAVEDTQKYGQAIGHIGKLA----AGSLKVGDAVQ 549

  Fly   642 LQVDAQQRQLNTCHHTATHLLNAAIRSLFKKVTYQVSSSVSSDQCKLELGLLGKRIQKTDVQLIE 706
            ..||..:|.....:|:||||::||:|.:......|..|.|:....:.:.. ..:.::..:::.:|
E. coli   550 ADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFS-HNEAMKPEEIRAVE 613

  Fly   707 DLINRVICSAAPVEVQLLSAAEVLEQNDITMVPGEVYPEQGLRLVNVESPELQLSSKELCCGTHA 771
            ||:|..|....|:|..::. .|..:......:.||.|.|: :|::::..     .|.|||.||||
E. coli   614 DLVNTQIRRNLPIETNIMD-LEAAKAKGAMALFGEKYDER-VRVLSMGD-----FSTELCGGTHA 671

  Fly   772 TNTSELSCFCIVNLKQTNRARFAFTAVAGQAA--------ENVLKTAALLRHRVDLLEKQFQTDK 828
            :.|.::..|.|::...|........||.|:.|        :.:.:.|.||:...:.|     .||
E. coli   672 SRTGDIGLFRIISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNL-----ADK 731

  Fly   829 LTNATEAELQTIRHNMLHTDIKLPYAFKMDTLERITEMLKR---IKDSSRTTLKEFVDVEMRTLL 890
            :.:..|...|                     ||:..:.||.   .::|:..:.|. :||....||
E. coli   732 VRSVLERTRQ---------------------LEKELQQLKEQAAAQESANLSSKA-IDVNGVKLL 774

  Fly   891 QEKPLDTHPFILHYITSSALVEEIPLQRATKLCPDRPILVISVCDSVVKARCCVPEKCITEKFNA 955
            ..:.....|.:|.     .:|:::..|..:.:     |::.:|.:..|.....| .|.:|::..|
E. coli   775 VSELSGVEPKMLR-----TMVDDLKNQLGSTI-----IVLATVVEGKVSLIAGV-SKDVTDRVKA 828

  Fly   956 SAWLQSFADTFNGQ------IAAPKGQN----PQAVCNMKG 986
            ...:...|....|:      :|...|.:    |.|:.::||
E. coli   829 GELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKG 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AlaRS-m	NP_523932.2	PLN02900	13..1010	CDD:215487	298/1016 (29%)
alaS	NP_417177.1	AlaS	3..875	CDD:439784	298/1016 (29%)