Protein Alignment AlaRS-m and aars2

DIOPT Version :10

• Sequence 1: NP_523932.2
• Gene: AlaRS-m / 38595
• FlyBaseID: FBgn0028962
• Length: 1012
• Species: Drosophila melanogaster
• Sequence 2: XP_001332388.5
• Gene: aars2 / 792787
• ZFINID: ZDB-GENE-041008-213
• Length: 1004
• Species: Danio rerio
• Alignment Length: 998
• Identity: 359/998 - (35%)
• Similarity: 501/998 - (50%)
• Gaps: 101/998 - (10%)

  Fly     9 QRVLTAREIRKTFLDHFTVNHGHKFVRSSPVVPFCDPTVAFVNAGMNQFKSVFLGTA-----AAP 68
            :|..|::.:|:.|:|.|...:||:.|.||.|.|..||::.||||||||||.:.||.|     ...
Zfish    39 RREFTSKRVRRKFIDFFREGYGHRVVPSSSVRPRGDPSLLFVNAGMNQFKPILLGCADPRSEMVS 103

  Fly    69 HKRVVNSQKCVRVGGKHNDLSVVGTDGYHHTFFEMLGNWSFGDYFKREACAMALELLRGPYNIDP 133
            ::||||||||||.|||||||..||.|.|||||||||||||||||||.||||||..||...|.|..
Zfish   104 YRRVVNSQKCVRAGGKHNDLQDVGKDVYHHTFFEMLGNWSFGDYFKVEACAMAWRLLTEEYGIPA 168

  Fly   134 GRLYVTYFAGDKVLGIPADLECFEIWRSLGFPASRILPFGCADNFWEMGATGPCGPCTEIHIDHR 198
            .||||:||:||...|:|||.|..:||.|:|..|..:||||..|||||||.|||||||||||.||
Zfish   169 QRLYVSYFSGDPANGLPADEETRDIWLSMGLRADHVLPFGMKDNFWEMGETGPCGPCTEIHYDH- 232

  Fly   199 PDLGSVEQRAKLVNAGRSDLTELWNLVFIQYNRHADGSISQLPAHHVDTGMGFERLTAVLQNKSS 263
              :|: ...|.||||...|:.|:|||||:||||.::||:..||...||||||.|||..|||.|.|
Zfish   233 --IGN-RNAALLVNADSPDVVEIWNLVFMQYNRESNGSLRALPQCSVDTGMGLERLVTVLQGKRS 294

  Fly   264 NYDTDLFTPIFDGIQQAAKTPVYSGSFPDGGNAAVLDTSYRILADHARMVTACLADGMLPDQ--- 325
            |||||||||:...|.|.:|.|.|.|. ....:.|.||.:||::|||.|.:..|:|||:.|..
Zfish   295 NYDTDLFTPLLSAIHQCSKAPAYQGR-TGAADVAQLDMAYRVVADHIRTICVCIADGVYPGMAGA 358

  Fly   326 NQKLRRVLRKALNISEHVF-AHDKLLTQLVPIVVETLGEAYPEMAAKQQAVIDLICHEQEVYKNL 389
            ...|||:||:|:..|..|. |.:..|..|||.|...||:||||:..:...::|||...:..:.:.
Zfish   359 ELVLRRILRRAVRFSTEVLQAPEGALASLVPTVAHLLGDAYPELNTESDRIMDLINQNEAHFLSS 423

  Fly   390 RESSSKAFAEVLMEFPNLDDIDLMECPGFVPAYRELQMQRCKFSNNTIPGDFLYKLTDTYGLTEE 454
            .:...:.....|   .|:|     |...|.||.....:.|    |...|.|.:..:.:..|
Zfish   424 LKQGRRVIDRTL---SNMD-----ENSSFFPASVAWSLYR----NLGFPLDLIDLMLEEKG---- 472

  Fly   455 SFLKLAELENMNCDLERYRAEVSLAKLKAKGNQRETAGGSLCDLATEQRIAEAQAMLTKRLTPTD 519
               |:.:.:.|....:.|.      ||   |.|.|...|...|......:||.|   .:|:..||
Zfish   473 ---KIVDKKEMKVLEDEYE------KL---GLQSEEDEGEKLDQLDLHSLAELQ---RQRVPHTD 522

  Fly   520 NSHKYTYSFDKESDSYQIPPLKTRVLGMLLNDAEVSRT-QGSRIQQPFTDLISIVTAGSNFYYES 583
            :|.||.||...:. .|...|.|..||.:..:.|.||.. ||..        .:::...::||.|.
Zfish   523 DSPKYCYSVGSDG-QYVFEPCKASVLALYCDGALVSEVRQGQH--------CAVILDQTSFYAEQ 578

  Fly   584 GGQQSDGGKILVSNHQQPDHPHSLDVIGVKHLNDCVVHICKLSSPTDAFQLAIGDEVELQVDAQQ 648
            |||.:|.|.......|....|    |..|:.....|||     ..|.|..|..||:|.|.||...
Zfish   579 GGQANDQGYFTKDGLQDVLFP----VKCVRLAGGYVVH-----KVTAAETLRTGDQVHLHVDEAW 634

  Fly   649 RQLNTCHHTATHLLNAAIRSLFKKVTYQVSSSVSSDQCKLELGLLGKRIQKTDVQLIEDLINRVI 713
            |.....:|||||:||.|:|.|...:..|..|..|:::.:.:..:.| .:..:::|.:|:|:..:|
Zfish   635 RLGCMINHTATHVLNFALRELLGPIVSQRGSHCSANRLRFDFSVKG-TLTVSELQKVEELVLNII 698

  Fly   714 CSAAPV---EVQLLSAAEVLEQNDITMVPGEVYPEQGLRLVNVESPELQL--------SSKELCC 767
            ...|.|   ||.|.||.::.....:    .|:||:. :|:|:|..|...|        :|.||||
Zfish   699 RQNADVHVEEVPLSSAKQIAGLRTV----DELYPDP-VRVVSVAVPVSDLLASERAEQTSVELCC 758

  Fly   768 GTHATNTSELSCFCIVNLKQTNRARFAFTAVAGQAAENVLKTAALLRHRVDLLEKQFQTDKLTNA 832
            |||...|..:..|.:|:.:|..:......|..|..|....:....|:..::.||.:.......:.
Zfish   759 GTHLLRTGAIRDFVVVSERQMMKGVCRIVAFTGDDAIKAREAGQALQEELESLEARMGLSNTLSI 823

  Fly   833 TEAE--LQTIRHNMLHTDI-KLPYAFKMDTLERITEMLKRIKDSSRTTLKEFVDVEMRTLLQEKP 894
            .||:  .:.:.|.:...|| .:|...:::...|:..|||    ||..:::: ::::...|..::.
Zfish   824 QEAKRLSKEVGHLINAVDITPMPQWKRLELQTRLKAMLK----SSNNSIRK-LEIKEAALKAKEL 883

  Fly   895 LDTH---PFILHYI-TSSALVEEIPLQRATKLCPDRPILVISVCDSVVKARCCVPEKCITEK--- 952
            ||.|   |.::..| |.|..|....:.:.:|..|...:::.|..:|..|..|.    |:..|
Zfish   884 LDKHSNKPVVVDLIQTDSISVLMKTVVQLSKSTPKSLVMLFSHWESSGKLLCA----CLVPKGST 944

  Fly   953 -FNASAWLQSFADTFNGQIAAPK 974
             .:|..|..|......|.....|
Zfish   945 GGSAIEWALSVCSRLGGNAEGAK 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AlaRS-m	NP_523932.2	PLN02900	13..1010	CDD:215487	358/994 (36%)
aars2	XP_001332388.5	PLN02900	41..993	CDD:215487	358/996 (36%)