DRSC/TRiP Functional Genomics Resources

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Protein Alignment AlaRS-m and cdc23

DIOPT Version :9

Sequence 1:NP_523932.2 Gene:AlaRS-m / 38595 FlyBaseID:FBgn0028962 Length:1012 Species:Drosophila melanogaster
Sequence 2:NP_957227.1 Gene:cdc23 / 393907 ZFINID:ZDB-GENE-040426-866 Length:579 Species:Danio rerio


Alignment Length:462 Identity:79/462 - (17%)
Similarity:156/462 - (33%) Gaps:149/462 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   361 LGEAYPEMAAKQQAVIDLICHEQEVYKNLRES----SSKAFAEVLMEFPNLDDIDLMECPGFVPA 421
            :...|.|:...::|:        :.|::|.|:    ||...:::.:.:.|:.|||..     :..
Zfish   217 MAHMYTELQMIKEAL--------QKYQSLMEAGFAKSSYIISQIAVAYHNIRDIDQA-----LYL 268

  Fly   422 YRELQMQRCKFSNNTIPGDFLYKLTDTYG--LTEESFL-KLAELENMNCDLERYRAEVSLAKLKA 483
            :.||:.|          ..|..:..||:.  |...|.. :|:.|.:...::::||.|.....   
Zfish   269 FNELREQ----------DPFRIENMDTFSNLLYVRSMKPELSYLAHNLVEIDKYRVETCCVI--- 320

  Fly   484 KGNQRETAGGSLCDLATEQRIAEAQAMLTKRLTP------TDNSHKYTYSFDKESDSYQIPPLKT 542
                     |:...|.::...|........:|.|      |...|:|   .:.::.|..|...:.
Zfish   321 ---------GNYYSLRSQHEKAALYFQRALKLNPRCLGAWTLMGHEY---MEMKNTSAAIQAYRH 373

  Fly   543 RVLGMLLNDAEVSRTQ-------GSR---IQQPFTDLISIVTAGSNFYYESGGQ-QSDGGKILVS 596
            .:        ||::..       |..   ::.||..|         :||....| :.:..::||:
Zfish   374 AI--------EVNKRDYRAWYGLGQTYEILKMPFYSL---------YYYRKAHQLRPNDSRMLVA 421

  Fly   597 NHQQPDHPHSLDVIGVKHLNDCVVHICKLSSPTDAFQLAIGDEVELQVDAQQRQLNTCHHTATHL 661
                              |.:|..   |||                    ||.:...|:..|..:
Zfish   422 ------------------LGECYE---KLS--------------------QQLEAKKCYWRAYSV 445

  Fly   662 LNAAIRSLFK--KVTYQVSSSVSSDQCKL----ELGLLGKRIQKTDVQLIEDLINRVICSAAPVE 720
            .:....:|.|  |:..|::.|..:.||.:    ::...|::::..:|......:.:........:
Zfish   446 GDVERMALLKLAKLHEQLNESDDAAQCYIIYIQDIFSCGEQLEHAEVSTALRYLGQYYFKNKLYD 510

  Fly   721 VQLLSAAEVLEQNDITMVPGEVYPEQG---LRLVNVESPELQLSSKELCCGTHATNTSELSCFCI 782
            ...|.|....:.||..        |:|   ||.::....:.:.||            ::||..|:
Zfish   511 EASLCAQRCCDYNDAR--------EEGKALLRQISAVREQGEPSS------------TDLSLPCV 555

  Fly   783 VNLKQTN 789
            .|....|
Zfish   556 FNPLSNN 562

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AlaRS-mNP_523932.2 PLN02900 13..1010 CDD:215487 79/462 (17%)
AlaRS_core 14..261 CDD:238360
tRNA_SAD 570..>667 CDD:298782 14/97 (14%)
tRNA_SAD 748..>784 CDD:197931 7/35 (20%)
cdc23NP_957227.1 ANAPC8 11..137 CDD:281973
TPR repeat 314..342 CDD:276809 4/39 (10%)
TPR repeat 347..377 CDD:276809 5/40 (13%)
TPR_11 350..413 CDD:290150 14/82 (17%)
TPR_1 350..381 CDD:278916 7/41 (17%)
TPR repeat 382..410 CDD:276809 6/36 (17%)
TPR repeat 416..444 CDD:276809 11/68 (16%)
TPR repeat 450..473 CDD:276809 6/22 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0013
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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