DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AlaRS-m and CG10802

DIOPT Version :9

Sequence 1:	NP_523932.2	Gene:	AlaRS-m / 38595	FlyBaseID:	FBgn0028962	Length:	1012	Species:	Drosophila melanogaster
Sequence 2:	NP_570062.1	Gene:	CG10802 / 31318	FlyBaseID:	FBgn0029664	Length:	436	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	94/404 - (23%)
Similarity:	152/404 - (37%)	Gaps:	72/404 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   528 FDKESDSYQIPPLKTRV-------LGMLLNDAEVSRTQGSRIQQPFTDLISIVTAGSNFYYESGG 585
            |..:.||: :...||::       |.......:|.:.:|          .:::...:..:.|.||
  Fly     3 FKCQEDSF-LKEFKTKIVSSEFATLDWTDPSGKVEKLKG----------FNVICEDTILFPEGGG 56

  Fly   586 QQSDGGKILVSNHQQPDHPHSLDVIGVKHLNDCVVHICKLSSPTDAFQLAIGDEVELQVDAQQRQ 650
            |..|.|.:           ....|..|:......||.  :.|||...|.|   ||.|.:|.|:|.
  Fly    57 QPCDYGTL-----------GGFPVKNVQRKGSTAVHF--VESPTSFEQDA---EVLLTLDYQRRL 105

  Fly   651 LNTCHHTATHLLNAAIRSLFK--KVTYQVSSSVSSDQCKLELGLLGKRIQKTDVQLIEDLINRVI 713
            .:...|:..||:.|.....||  ..::.:.|:||..|....     ..|.:..:.|||...|.:|
  Fly   106 DHMQQHSGQHLITALFDREFKYDTTSWSLGSTVSYIQLSTP-----HLISRESLDLIERQANDLI 165

  Fly   714 CSAAPVEVQLLSAAEVLEQNDITMVPGEVYPEQGL-RLVNVESPELQLSSKELCCGTHATNTSEL 777
            .....|.|.|:......|..|.....|.....:|| |:|.:|..|     ..:|||||.||.|:|
  Fly   166 REGREVTVLLVDPEVAQEFQDARAPRGLPKDHEGLARVVRIEGIE-----SNMCCGTHVTNLSQL 225

  Fly   778 SCFCIVNLKQTNRARFAFTAVAGQAAENVLKTAALLRHRVDLLEKQFQTDKLTNATEAELQTIRH 842
            .|..::..::. :|......|.|   |.||.....:..|    |:|. |..|.......|:.::
  Fly   226 QCIKLLYAEKV-KANVLVHFVVG---ERVLVKLGEVFQR----EQQL-TQALKGGPGQHLELVQ- 280

  Fly   843 NMLHTDIKLPYAFKMDTLER-ITEMLKRIKDSSRTTLKEFVDVEMR---------TLLQEKPLDT 897
             .|..::|....:....|:| .|...:|:.|..:....::..:..|         |.|:..|
  Fly   281 -KLQQNVKGSRKYFQQLLKRYATAEAERLCDLPKKDRPKYFSLHRRDGIEVDFINTFLRAAP--- 341

  Fly   898 HPFILHYITSSALV 911
             ..|.:::|.|..|
  Fly   342 -EGIFYFLTVSESV 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AlaRS-m	NP_523932.2	PLN02900	13..1010	CDD:215487	94/404 (23%)
		AlaRS_core	14..261	CDD:238360
		tRNA_SAD	570..>667	CDD:298782	25/96 (26%)
		tRNA_SAD	748..>784	CDD:197931	15/36 (42%)
CG10802	NP_570062.1	AlaX	6..250	CDD:225427	70/284 (25%)
CG10802	NP_570062.1	tRNA_SAD	43..229	CDD:298782	59/211 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840