Protein Alignment AlaRS-m and AlaRS

DIOPT Version :10

• Sequence 1: NP_523932.2
• Gene: AlaRS-m / 38595
• FlyBaseID: FBgn0028962
• Length: 1012
• Species: Drosophila melanogaster
• Sequence 2: XP_061510729.1
• Gene: AlaRS / 1279087
• VectorBaseID: AGAMI1_013865
• Length: 967
• Species: Anopheles gambiae
• Alignment Length: 1025
• Identity: 348/1025 - (33%)
• Similarity: 485/1025 - (47%)
• Gaps: 142/1025 - (13%)

  Fly    12 LTAREIRKTFLDHFTVNHGHKFVRSSPVVPFCDPTVAFVNAGMNQFKSVFLGTA-----AAPHKR 71
            |||.:||..|||.|.... |.:|.||.|:|..|||:.|.||||||||.:||||.     .|...|
Mosquito     5 LTASQIRSIFLDFFKEKE-HLYVHSSSVIPLDDPTLLFANAGMNQFKPIFLGTVDPNSDMAKWVR 68

  Fly    72 VVNSQKCVRVGGKHNDLSVVGTDGYHHTFFEMLGNWSFGDYFKREACAMALELLRGPYNIDPGRL 136
            ..|:|||:|.|||||||..||.|.|||||||||||||||||||:|.|..|.|||.....:...||
Mosquito    69 TANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGNWSFGDYFKKEICTWAWELLTERLKLPKERL 133

  Fly   137 YVTYFAGDKVLGIPADLECFEIWRSLGFPASRILPFGCADNFWEMGATGPCGPCTEIHIDHRPDL 201
            |||||.|....|:..||||.|||..||.....|||....|||||||.|||||||:|:|.|.   :
Mosquito   134 YVTYFGGHPESGLEPDLECREIWLKLGVKEEHILPGSMKDNFWEMGETGPCGPCSELHFDR---I 195

  Fly   202 G--SVEQRAKLVNAGRSDLTELWNLVFIQYNRHADGSISQLPAHHVDTGMGFERLTAVLQNKSSN 264
            |  ||.:   |||....|:.|:||||||||||..|.|:..||..|:|.|||||||.:|:|:|.||
Mosquito   196 GGRSVPE---LVNMDDPDVLEIWNLVFIQYNREQDSSLKLLPKKHIDCGMGFERLVSVIQDKRSN 257

  Fly   265 YDTDLFTPIFDGIQQAAKTPVYSGSF----PDGGNAAVLDTSYRILADHARMVTACLADGMLPDQ 325
            ||||:|.|:||.||:......|.|..    .||     :|.:||:||||||.:|..||||..||.
Mosquito   258 YDTDVFMPLFDAIQKGTGAAAYQGRVGADDSDG-----VDMAYRVLADHARTITIALADGGFPDN 317

  Fly   326 NQK---LRRVLRKALN-ISEHVFAHDKLLTQLVPIVVETLGEAYPEMAAKQQAVIDLICHEQEVY 386
            ..:   |||:||:|:. .:|.:.|.......||..||:.|||.:||:....|.:
Mosquito   318 TGRGYVLRRILRRAVRYATEKLNAKPGFFATLVDTVVQLLGETFPEVRKDPQHI----------- 371

  Fly   387 KNLRESSSKAFAEVLMEFPNLDDIDLMECPGFVPAYRELQMQRCKFSNN-TIPGDFLYKLTDTYG 450
            ||:.....:.|.:.|....||                 |.....|..|: .||||..::|.||||
Mosquito   372 KNVINEEEQQFLKTLTRGRNL-----------------LNRTIAKLGNSKVIPGDVAWRLYDTYG 419

  Fly   451 LTEESFLKLAELENMNCDLERYRAEVSLAKLKAKGNQRETAGGSLCDLATEQRIAEAQAMLTKRL 515
            ...:..|.:||.:.|..|:|.|......:.:.::|.::........|:   ..|:|.|   .:::
Mosquito   420 FPIDLTLLMAEEKQMTIDMEGYEKAKHESYIISQGKEKSKTATIDLDV---HGISELQ---ERKV 478

  Fly   516 TPTDNSHKYTY---SFDKESDSYQIPPLKTRVLGMLLNDAEVSRTQGSRIQQPFTDLISIVTAGS 577
            ..||:|.||.|   |.|..: .|...|...:::.:..|:|.|...|..:       ...::...:
Mosquito   479 PATDDSFKYRYKAESIDPLA-QYVFEPCTGKIVALRFNNAFVEEVQAGQ-------ECGVILDRT 535

  Fly   578 NFYYESGGQQSDGGKILVSNHQQPDHPHSLDVIGVKHLNDCVVHICKLSSPTDAFQLAIGDEVEL 642
            |||.|||||..|.|.::..|.:..:...||    |.:....|:||..:..     .|.:||||..
Mosquito   536 NFYAESGGQIYDQGFLVKVNDESSEFNVSL----VYNRGGYVLHIGVVEG-----TLRVGDEVHC 591

  Fly   643 QVDAQQRQLNTCHHTATHLLNAAIRSLFKKVTYQVSSSVSSDQCKL--------------ELGLL 693
            .:|..:|||...:|:|||.||.::..:..:.|.|..|.|..::.:.              |...|
Mosquito   592 HMDVVRRQLTMKNHSATHALNHSLLKVLGQDTDQRGSLVVPEKLRFDFTNKSAMTIEQVAEAERL 656

  Fly   694 GKRIQKTDVQLIEDLINRVICSAAPVEVQLLSAAEVLEQNDITMVPGEVYPEQGLRLVNVESPEL 758
            .:.:.|.:||:.....|             |:.|:.:  ..:..|..||||:. :|:::...|..
Mosquito   657 TREVVKRNVQVYAKEAN-------------LAVAKTI--RGLRSVFDEVYPDP-VRVISFGVPVE 705

  Fly   759 QL-----------SSKELCCGTHATNTSELSCFCIVNLKQTNRARFAFTAVAGQAAENVLKTAAL 812
            ||           :|.|.|.|||...:..:..|.|...:...:......|:.|..|...||...|
Mosquito   706 QLEADPTGEAGVINSVEFCGGTHLHQSGHMVDFVITTEEAIAKGIRRIVALTGPEALKALKKTEL 770

  Fly   813 LRHRVDLLEKQFQTDKLTNATEAELQTIRHNMLHTDIK---LPYAFKMDTLERITEMLKRIKDSS 874
            |...:..|......||  ...||:....:...|..|:.   :||. |.|.|..:.:.||:..|..
Mosquito   771 LEQELSKLRATIDGDK--EGREAKEHVKKIIELTDDVSQATIPYV-KKDELRTVLKGLKKALDDK 832

  Fly   875 RTTLKEFVD---VEMRTLLQEKPLDTHPFILHYI----TSSALVEEIPLQRATKLCPDRPILVIS 932
            ....:..|.   ||....|.:...|. ||::..:    .:.||  :..|:...|:.|::..|.:|
Mosquito   833 ERVARAAVASGVVEKAKELSQAHKDA-PFLVQRLEALNNTKAL--DSALKEVRKVNPEQSALFLS 894

  Fly   933 VCDSVVKARC--CVPEKCITEKFNASAWLQSFADTFNGQIAAPKGQNPQA 980
            |.:...|..|  .||:..:.:...|:.|:...|....|: ...|.::.||
Mosquito   895 VDEDSKKIFCLASVPKSAVDKGLKANEWISHIAPVMGGK-GGGKPESAQA 943

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AlaRS-m	NP_523932.2	PLN02900	13..1010	CDD:215487	347/1024 (34%)
AlaRS	XP_061510729.1	None