DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gen and AT3G48900

DIOPT Version :9

Sequence 1:	NP_647943.2	Gene:	Gen / 38594	FlyBaseID:	FBgn0263831	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_001118795.1	Gene:	AT3G48900 / 824051	AraportID:	AT3G48900	Length:	600	Species:	Arabidopsis thaliana

Alignment Length:	591	Identity:	145/591 - (24%)
Similarity:	236/591 - (39%)	Gaps:	156/591 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGVKELWGVLTPHCERKPINELRGKKVAIDLAGWVCESLNVVDYFVHPRH--HLKNLFFRTCYLI 63
            ||||.||.||.|..:..|::.|:.|:|.:||:.|:.|...|...:...:.  :|:..|.|...||
plant     1 MGVKYLWDVLEPCKKTFPLDHLQNKRVCVDLSCWMVELHKVNKSYCATKEKVYLRGFFHRLRALI 65

  Fly    64 WEQVTPVFVLEGVAPKLKSQVIAKRNELQFR----GVKPKNSPECTQSQPSKGDKGRSRFNHVLK 124
            ....:.:.|.:|..|.:|.....:|.:.:|.    ||:|...   |..:.:.|    |.|:.::|
plant    66 ALNCSIILVSDGAIPGIKVPTYKRRLKARFEIADDGVEPSKE---TSLKRNMG----SEFSCIIK 123

  Fly   125 QCETLLLSMGIQCVQGPGEAEAYCAFLNKHGLVDGVISQDSDCFAYGAVRVYRNFSVSTQGAQAA 189
            :.:.:..::||.|:.|..||||.||.||...|.|...|.|||.|.:||..|||...:       .
plant   124 EAKVIASTLGILCLDGIEEAEAQCALLNSESLCDACFSFDSDIFLFGAKTVYREICL-------G 181

  Fly   190 AGGAVDIYDMREITSRMDFGQQKIIVMALLCGCDYCPDGIGGIGKDGVLKLFNKYKETEILDRMR 254
            .||.|..|:|.:|..::..|:..:|.:|||.|.|| ..|:.|:.::...:|.....:..||:::.
plant   182 EGGYVVCYEMDDIKKKLGLGRNSLIALALLLGSDY-SQGVRGLRQEKACELVRSIGDNVILEKVA 245

  Fly   255 SWRG----ETDKYNALEIRVDDKSICSNCGHIGKTQSHTKSGCSVCRTHKGCDESLWKEQRLSIK 315
            | .|    |..:.:..::|   .|:||.                                    |
plant   246 S-EGLSFAEKPRKSKKQVR---PSVCSK------------------------------------K 270

  Fly   316 SELTLRRKALLSPDFPNEEIIAEFLSEPDTIPNLNLNWRQPN-----LVKF------IKQIGH-L 368
            ..|.|   .:::.:..:.|.:.|.....|...|...:....|     |.:|      :::|.| .
plant   271 GTLPL---VVINGNNRDPERLEEIKQVIDAFMNPKCHQADSNTVSRALAEFSFQRTKLQEICHQF 332

  Fly   369 LQWPEIYCFQKFFP-----ILTRWQVQQSKQEKI-----LIQPH--------EIIKKRTVKGVPS 415
            .:||.....:...|     .|.|:...||:..::     |.:|.        ||||.|.|:|...
plant   333 FEWPPEKTDEYILPKVAERNLRRFANLQSRSTEVEVNLPLHKPQMPEKCPVSEIIKTRKVQGREC 397

  Fly   416 LELRWHDPSGIFKGLIPDKQIAEYEAEHPKGIEELYYTIEPLDMLETAYPDLVAAF---LKSKEK 477
            .|:.|:|                        :|.|..:|.|.|::|.|.|:.:..|   :.:|:|
plant   398 FEVSWND------------------------LEGLESSIVPADLVERACPEKIIEFKEKMAAKKK 438

  Fly   478 PAKKTTRKKKTAS------------------------------EEENKENE-PNSKPKRVVRKIK 511
            ..|...::|:|:|                              ||..:||| .|||....:|.|.
plant   439 KPKPKQKQKETSSPTKSSSLVELSLELQHLDLNSTSLVSRSTLEEAEQENEQQNSKKHDYLRLID 503

  Fly   512 AQPEEN 517
            :...||
plant   504 SPDREN 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gen	NP_647943.2	PIN_GEN1	1..385	CDD:189039	102/410 (25%)
Gen	NP_647943.2	H3TH_GEN1	210..342	CDD:188625	24/135 (18%)
AT3G48900	NP_001118795.1	PIN_GEN1	2..203	CDD:350217	67/214 (31%)
		rad2	<105..365	CDD:273166	74/317 (23%)
		Chromo_2	385..429	CDD:408481	18/67 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	68	1.000	Domainoid score	I3491
eggNOG	1	0.900	-	-		E1_COG0258
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094524at2759
OrthoFinder	1	1.000	-	-		FOG0005192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11081
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4810
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.920