Protein Alignment Gen and ercc5

DIOPT Version :9

• Sequence 1: NP_647943.2
• Gene: Gen / 38594
• FlyBaseID: FBgn0263831
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: XP_003197653.2
• Gene: ercc5 / 541502
• ZFINID: ZDB-GENE-050327-28
• Length: 1010
• Species: Danio rerio
• Alignment Length: 463
• Identity: 92/463 - (19%)
• Similarity: 177/463 - (38%)
• Gaps: 90/463 - (19%)

  Fly    65 EQVTPVFVLEGVAPKLKSQVIAKRNELQFRGVKPKNSPECTQSQPSKGDKGRSRF-NHVLKQCET 128
            :|:..|......||.:.........|||....:.::..:..:.|..:..:..|.. ..:.::.:.
Zfish   600 DQIEDVDESVNEAPAVSEWEHIDTEELQLLDRELQDEQQTLREQHQQQQRSSSTVTGQMCQESQE 664

  Fly   129 LLLSMGIQCVQGPGEAEAYCAFLNKHGLVDGVISQDSDCFAYGAVRVYRNFSVSTQGAQAAAGGA 193
            ||...|:..:..|.||||.||.|::.....|.|:.|||.:.:|...|||||....:        .
Zfish   665 LLRLFGVPFIVAPMEAEAQCAALDRLDQTHGTITDDSDIWLFGGRHVYRNFFNQNK--------Y 721

  Fly   194 VDIYDMREITSRMDFGQQKIIVMALLCGCDYCPDGIGGIGKDGVLKLFNKYKET--EILDRMRSW 256
            |:.|.:.::.:::...:.|:|.:|.|.|.|| .:||.|:|....:::.|::...  |.|.::..|
Zfish   722 VEHYQIVDMQNQLGLDRSKLINLAYLLGSDY-TEGIPGVGYVTGMEILNEFPGAGLEPLVQLSEW 785

  Fly   257 RGETDKYNALEIRVDDKSICSNCGHIGKTQSHTKSGCSVCRTHKGCDESLWKEQRLSIKSELTLR 321
            ..|..:...|.:...|                ||                       :|.:|
Zfish   786 WTEAQENKKLSVNPKD----------------TK-----------------------VKKKL--- 808

  Fly   322 RKALLSPDFPNEEIIAEFLSEPDTIPNLNLNWRQPNLVKFIKQIGHLLQWPEIYCFQKF------ 380
            |...:.|.|||..:...:|.......:.:.:|.:|:| ..||:          :|..:|
Zfish   809 RNLQIHPGFPNPAVAQAYLQPSVDQSDASFSWGRPHL-DLIKE----------FCQSRFGWSSRK 862

  Fly   381 -----FPILTRWQVQQSKQEKILIQPHEIIKKRTVKGVPSLELRWHDPSGIFKGLIPDKQIAEYE 440
                 .|:|.:   .||:|.::.|.....::::..:.:.|..||        :.:|..|:....|
Zfish   863 TEETLQPVLKQ---LQSQQTQLRIDSFFRLEQQDRQQIRSERLR--------RAVICMKRKEREE 916

  Fly   441 AEHPKGIEELYYTIEPLDMLETAYPDLVAAFLKSKEKPAKKTTRKKKTASEEENKENEPNSKPKR 505
            .|..:.:..........|  |...| |...|:.|..:.:.:....|:..:|..:..:|..::..:
Zfish   917 EEEDESVSAQKQGRSEAD--EAPGP-LAGGFISSDPQTSTQGGGAKQIRAESSSSSSEEEAESGK 978

  Fly   506 VVRKIKAQ 513
            .|..:.|:
Zfish   979 GVAMVTAR 986

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gen	NP_647943.2	PIN_GEN1	1..385	CDD:189039	69/333 (21%)
		H3TH_GEN1	210..342	CDD:188625	28/133 (21%)
ercc5	XP_003197653.2	rad2	1..909	CDD:273166	78/381 (20%)
		PIN_XPG	1..>120	CDD:189038
		PIN_SF	<626..872	CDD:301351	64/307 (21%)
		H3TH_XPG	740..832	CDD:188624	28/134 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0258
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094524at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820