Protein Alignment Gen and gen-1

DIOPT Version :9

• Sequence 1: NP_647943.2
• Gene: Gen / 38594
• FlyBaseID: FBgn0263831
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_498361.1
• Gene: gen-1 / 175885
• WormBaseID: WBGene00020442
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 122/546 - (22%)
• Similarity: 199/546 - (36%)
• Gaps: 150/546 - (27%)

  Fly     1 MGVKELWGVLTPHCERKPINE-LRGKKVAIDLAGWVCESLNVVDYFVH----PRHHLKNLFFRTC 60
            |.:..:| ....|..||..|| :|.|.::||...|:.|||...:  .|    |..:|...|.|..
 Worm     1 MTINGIW-EWANHVVRKVPNETMRDKTLSIDGHIWLYESLKGCE--AHHQQTPNSYLVTFFTRIQ 62

  Fly    61 YLIWEQVTPVFVLEGVAPKLKSQVIAKRNELQFRGVKPKNSPECTQSQPSKGDKGRSRF-NHVLK 124
            .|:..::.|:.|.:.:.....:.....:||.            ..:.:.|.||...:.. :||.|
 Worm    63 RLLELKIIPIVVFDNINASSSAHESKDQNEF------------VPRKRRSFGDSPFTNLVDHVYK 115

  Fly   125 QCETLLLSMGIQCVQGPGEAEAYCAFLNKHGLVDGVISQDSDCFAYGAVRVYR-NFSVSTQGAQA 188
             ...||..:||:.:..||:.||.||.|...|:..|.|:.|.|.|.:|...:|| :|:..|.....
 Worm   116 -TNALLTELGIKVIIAPGDGEAQCARLEDLGVTSGCITTDFDYFLFGGKNLYRFDFTAGTSSTAC 179

  Fly   189 AAGGAVDIYDMREITSRMDFGQQKI-----IVMALLCGCDYCPDGIGGIGKDGVLKLFNKY---- 244
                   ::|:..::....|.::|:     |..|:|.||||...|:..||...|..:..::
 Worm   180 -------LHDIMHLSLGRMFMEKKVSRPHLISTAILLGCDYFQRGVQNIGIVSVFDILGEFGDDG 237

  Fly   245 -KETE---ILDRMRSWRGETDKYNALEIRVDDKSICSNCGHIGKTQSHTKSGCSVCRTHKGCDES 305
             :|.:   ||||..|:..|     .:..|.:|            ||
 Worm   238 NEEIDPHVILDRFASYVRE-----EIPARSED------------TQ------------------- 266

  Fly   306 LWKEQRLSIKSELTLRRKALLSP-DFPNEEIIAEFLSEPDTIPNLNLNWRQPNLVKFIKQIGHLL 369
                      .:|.||||....| .|||          .|.:.|....:.:|.:...|.:|
 Worm   267 ----------RKLRLRRKKYNFPVGFPN----------CDAVHNAITMYLRPPVSSEIPKI---- 307

  Fly   370 QWPEIYCFQKFFPILTR---WQVQQSKQEKILIQPHEIIKKRTVKGVPSLELRWHDPSGIFKGLI 431
             .|....||:...|:.:   |...::::|..|                |:..:.|..:.:.:..|
 Worm   308 -IPRAANFQQVAEIMMKECGWPATRTQKELAL----------------SIRRKVHLTTTVAQTRI 355

  Fly   432 PDKQIAEYEAEHPKGIEELYYTIEPLDMLETAYPDLVAAFLKSKEKPAKKTTRKKKTASEEEN-- 494
            ||    .:.|...|....:   :||.:.||    |.::         |..|..:|:..||...
 Worm   356 PD----FFAATKSKNFTPI---VEPCESLE----DYIS---------ANNTWMRKRKRSESPQIL 400

  Fly   495 ----KENEPNSKPKRVVRKIKAQPEE 516
                |...|:.|....:|..|..|.:
 Worm   401 QHHAKRQVPDRKRSVKIRAFKPYPTD 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gen	NP_647943.2	PIN_GEN1	1..385	CDD:189039	96/404 (24%)
		H3TH_GEN1	210..342	CDD:188625	32/145 (22%)
gen-1	NP_498361.1	PIN_SF	1..209	CDD:301351	58/230 (25%)
		H3TH_XPG	200..302	CDD:188624	34/157 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0258
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094524at2759
OrthoFinder	1	1.000	-	-		FOG0005192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820