DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Srp54k and AT5G49500

DIOPT Version :9

Sequence 1:	NP_523931.1	Gene:	Srp54k / 38593	FlyBaseID:	FBgn0010747	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_199761.1	Gene:	AT5G49500 / 835010	AraportID:	AT5G49500	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	253/514 - (49%)
Similarity:	368/514 - (71%)	Gaps:	25/514 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVLADLGRKITTALHSLSKATVINEEALNSMLKEICAALLEADVNIRLVKQLRENVRAVIDFDEM 65
            ||||:||.:|.:|:..::..|:|:|:|||..|.||..|||::||:..|||:::.|::.:::.:::
plant     1 MVLAELGGRIMSAIQKMNNVTIIDEKALNDCLNEITRALLQSDVSFPLVKEMQTNIKKIVNLEDL 65

  Fly    66 AGGLNKRRMIQSAVFKELVKLVDPGVKPYQPIKGKANVVMFVGLQGS--GKTTTCTKLAYHYQKR 128
            |.|.||||:|:.|:|.||.|::|||...:.|.|.|.:|||||||||.  .|......:....:::
plant    66 AAGHNKRRIIEQAIFSELCKMLDPGKSAFAPKKAKPSVVMFVGLQGEVLEKPQLVPSMLIIIRRK 130

  Fly   129 NWKSCLVCADTFRAGAYDQVKQNATKARIPFYGSYTEIDPVVIAQDGVDMFKREGFEMIIVDTSG 193
            .:|..|||||||||||:||:||||||::||:|||||..|||.||.:|||.||:|..::|||||||
plant   131 GYKPALVCADTFRAGAFDQLKQNATKSKIPYYGSYTGSDPVKIAVEGVDRFKKENCDLIIVDTSG 195

  Fly   194 RHKQEESLFEEMLAVSNAVSPDNIIFVMDATIGQACEAQAKAFKDKVDIGSVIITKLDGHAKGGG 258
            ||||:.||||||..:|.|..||.:|||||::|||....||:|||..|.:|:|||||:||||||||
plant   196 RHKQQASLFEEMRQISEATKPDLVIFVMDSSIGQTAFEQARAFKQTVAVGAVIITKMDGHAKGGG 260

  Fly   259 ALSAVAATQSPIIFIGTGEHIDDLEPFKTKPFVSKLLGMGDIEGLIDKVNE-LKLDGNDELLEKI 322
            .|||||||:||:||||||||:|:.|.|..|||||:|||.||:.|.::|:.| :..|...||||.:
plant   261 TLSAVAATKSPVIFIGTGEHMDEFEVFDAKPFVSRLLGNGDMSGFVNKLQEVVPKDQQPELLEML 325

  Fly   323 KHGHFTIRDMYEQFQNIMKMGPFSQFMNMIPGFSQDFMTKGGEQESMARVKRMMTMMDSMSDNEL 387
            .||.||:|.||:||||::.|||..:..:|:||...:.|.:|.|:||.|::||.|||||||::.||
plant   326 SHGKFTLRIMYDQFQNMLNMGPLKEVFSMLPGMRAEMMPEGHEKESQAKIKRYMTMMDSMTNEEL 390

  Fly   388 DNRDGAKLFSKQPNRCVRVAQGAGVMEREVKELIAHYTKFSAVVKKMGGVKGLFKQGDM---TKN 449
            |: ...|:|::  :|.:|:|:|:|.:.|||.|::..|.:.:.:..|:.|:|.| ::|:|   :||
plant   391 DS-SNPKVFNE--SRIMRIARGSGRIVREVMEMLEEYKRLTTMWGKVKGLKNL-EKGNMSALSKN 451

  Fly   450 VNPTQMAKLNQQIAKMIDPRMLQQMGGVGGIQNMMRQLQQGAAGGLGGLGNLMSGFGGK 508
            .|       :||::|::..:||:|:||:.|:|::|:|:..|.        :||..|||:
plant   452 KN-------SQQLSKVLPAQMLKQIGGMSGLQSLMKQMGSGK--------DLMGMFGGR 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srp54k	NP_523931.1	SRP54_euk	2..428	CDD:273615	225/428 (53%)
		SRP54_N	6..83	CDD:280954	31/76 (41%)
		SRP54	102..294	CDD:278855	122/193 (63%)
		SRP_SPB	327..428	CDD:281039	45/100 (45%)
AT5G49500	NP_199761.1	SRP54_euk	2..430	CDD:273615	225/430 (52%)
		SRP54_N	6..83	CDD:280954	31/76 (41%)
		SRP54	102..296	CDD:278855	122/193 (63%)
		SRP_SPB	329..426	CDD:281039	45/99 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	292	1.000	Domainoid score	I358
eggNOG	1	0.900	-	-		E1_COG0541
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	547	1.000	Inparanoid score	I257
OMA	1	1.010	-	-		QHG62209
OrthoDB	1	1.010	-	-		D463152at2759
OrthoFinder	1	1.000	-	-		FOG0002467
OrthoInspector	1	1.000	-	-		otm3147
orthoMCL	1	0.900	-	-		OOG6_100507
Panther	1	1.100	-	-	O	PTHR11564
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1645
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840