DRSC/TRiP Functional Genomics Resources

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Protein Alignment Con and Lrg1

DIOPT Version :9

Sequence 1:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:NP_084072.1 Gene:Lrg1 / 76905 MGIID:1924155 Length:342 Species:Mus musculus


Alignment Length:312 Identity:81/312 - (25%)
Similarity:131/312 - (41%) Gaps:69/312 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   190 IEYSQVEIVKSYAFANLPFLERIILNNNHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNL 254
            :|:|.:..:.:.|....|.|..:.|::|.:.||..:..|...|||.|:|..|        |.|:|
Mouse    68 VEFSNLTQLPAAALQGCPGLRELHLSSNRLQALSPELLAPVPRLRALDLTRN--------ALRSL 124

  Fly   255 PLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIG 319
            |                .|||:..|.|:.|.|..||:..::::..:||..|..|.|..|.|:.:.
Mouse   125 P----------------PGLFSTSANLSTLVLRENQLREVSAQWLQGLDALGHLDLAENQLSSLP 173

  Fly   320 DTVFAELWSLSELELDDNRIERISERALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQA 384
            ..:.|.|.:|..|:|..|.:|.:.|..|.|...|:.|:|..|.|:::::.||...|.|..:.:..
Mouse   174 SGLLASLGALHTLDLGYNLLESLPEGLLRGPRRLQRLHLEGNRLQRLEDSLLAPQPFLRVLFLND 238

  Fly   385 NKLETLTFYTFQ--------PIMDNLVNSTSELL----------------VSDNKFICD------ 419
            |:|..:...:||        .:.:|.::||...|                :|.|.:|||      
Mouse   239 NQLVGVATGSFQGLQHLDMLDLSNNSLSSTPPGLWAFLGRPTRDMQDGFDISHNPWICDKNLADL 303

  Fly   420 CRLQWIFELKNRTRHLQLRDSLEDLHCTLQEPKLSHFVDPVPPTILDVLNIG 471
            ||  |:  :.||.:..    |..|..|...|.....       .:|||..:|
Mouse   304 CR--WL--VANRNKMF----SQNDTRCAGPEAMKGQ-------RLLDVAELG 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 28/100 (28%)
LRR_8 183..243 CDD:290566 16/52 (31%)
leucine-rich repeat 185..208 CDD:275380 3/17 (18%)
leucine-rich repeat 209..232 CDD:275380 6/22 (27%)
LRR_RI <225..416 CDD:238064 56/214 (26%)
LRR_8 232..291 CDD:290566 18/58 (31%)
leucine-rich repeat 233..256 CDD:275380 8/22 (36%)
leucine-rich repeat 257..280 CDD:275380 3/22 (14%)
leucine-rich repeat 281..304 CDD:275380 7/22 (32%)
LRR_8 304..363 CDD:290566 19/58 (33%)
leucine-rich repeat 305..328 CDD:275380 7/22 (32%)
leucine-rich repeat 329..352 CDD:275380 8/22 (36%)
LRR_8 352..416 CDD:290566 19/87 (22%)
leucine-rich repeat 353..376 CDD:275380 7/22 (32%)
LRRCT 414..>450 CDD:214507 12/41 (29%)
Lrg1NP_084072.1 leucine-rich repeat 65..86 CDD:275380 3/17 (18%)
LRR_8 66..121 CDD:290566 16/60 (27%)
LRR_RI <74..294 CDD:238064 63/243 (26%)
leucine-rich repeat 87..110 CDD:275380 6/22 (27%)
LRR_8 109..169 CDD:290566 25/83 (30%)
leucine-rich repeat 111..134 CDD:275380 12/46 (26%)
leucine-rich repeat 135..158 CDD:275380 7/22 (32%)
leucine-rich repeat 159..182 CDD:275380 7/22 (32%)
LRR_8 162..217 CDD:290566 18/54 (33%)
leucine-rich repeat 183..206 CDD:275380 8/22 (36%)
LRR_8 205..265 CDD:290566 14/59 (24%)
leucine-rich repeat 207..230 CDD:275380 7/22 (32%)
leucine-rich repeat 231..254 CDD:275380 5/22 (23%)
leucine-rich repeat 255..278 CDD:275380 4/22 (18%)
LRRCT 292..338 CDD:214507 16/60 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167831252
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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