DRSC/TRiP Functional Genomics Resources

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Protein Alignment Con and lrig1

DIOPT Version :9

Sequence 1:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:XP_688817.4 Gene:lrig1 / 560325 ZFINID:ZDB-GENE-031113-23 Length:1022 Species:Danio rerio


Alignment Length:312 Identity:88/312 - (28%)
Similarity:144/312 - (46%) Gaps:60/312 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   142 LHQNDTTWTRFYQQKRLR-ELKFVIQNNARLDYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFAN 205
            |..|......|...|.|. .|:.:..:..||.::|...:| |..|:.:.:..:::.:::...|..
Zfish   161 LSSNKIVHLEFGAFKNLAGSLQILRLSRNRLTHLPVKGLE-LPKLTQLELSRNRLRLIEGLTFQG 224

  Fly   206 LPFLERIILNNNHIMALDQDAFANHIRLRELNLEHNQIFEMDR---YAFRNL------------- 254
            |..||.:.|..|:|..|...||....|:|.|:|::|.:.|::.   |...:|             
Zfish   225 LSSLEVLKLQRNNISKLTDGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNF 289

  Fly   255 -----PLCER---LFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLT 311
                 ..|||   |.|:.||::.|.||.||.:..|..|.|.||.|:.:|...||||.:|..|:|.
Zfish   290 NPEGWGFCERLRELNLSYNNLTKLSEGSFAKLVNLISLRLGHNSISHITEGAFRGLSSLRTLELD 354

  Fly   312 RNNLN-FIGDT--VFAELWSLSELELDDNRIERISERALDGLNTLKTLNLRNNLLKKIDNGLLRG 373
            .|::: .|.||  .|..|.:|::|.|..|:|:.::::|..||..|:.|||..|            
Zfish   355 HNDISGTIEDTSGAFTGLENLNKLTLFGNKIKSVAKKAFSGLEALEHLNLGEN------------ 407

  Fly   374 TPALLSINVQA-NKLETLTFYTFQPIMDNLVNSTSELLVSDNKFICDCRLQW 424
              |:.||..:| :|::.|.:                |.:..:.|:|||:|.|
Zfish   408 --AIRSIQPEAFSKMKNLRY----------------LHIQSDSFLCDCQLHW 441

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 45/168 (27%)
LRR_8 183..243 CDD:290566 16/59 (27%)
leucine-rich repeat 185..208 CDD:275380 3/22 (14%)
leucine-rich repeat 209..232 CDD:275380 8/22 (36%)
LRR_RI <225..416 CDD:238064 62/218 (28%)
LRR_8 232..291 CDD:290566 25/82 (30%)
leucine-rich repeat 233..256 CDD:275380 7/43 (16%)
leucine-rich repeat 257..280 CDD:275380 12/25 (48%)
leucine-rich repeat 281..304 CDD:275380 11/22 (50%)
LRR_8 304..363 CDD:290566 22/61 (36%)
leucine-rich repeat 305..328 CDD:275380 9/25 (36%)
leucine-rich repeat 329..352 CDD:275380 8/22 (36%)
LRR_8 352..416 CDD:290566 12/64 (19%)
leucine-rich repeat 353..376 CDD:275380 5/22 (23%)
LRRCT 414..>450 CDD:214507 6/11 (55%)
lrig1XP_688817.4 LRRNT 31..63 CDD:214470
leucine-rich repeat 63..84 CDD:275380
LRR_RI 77..334 CDD:238064 47/173 (27%)
LRR_8 83..142 CDD:290566
leucine-rich repeat 85..107 CDD:275380
leucine-rich repeat 108..131 CDD:275380
LRR_8 132..191 CDD:290566 6/29 (21%)
leucine-rich repeat 132..155 CDD:275380
leucine-rich repeat 156..180 CDD:275380 5/18 (28%)
leucine-rich repeat 181..203 CDD:275380 6/22 (27%)
LRR_8 202..262 CDD:290566 16/59 (27%)
leucine-rich repeat 204..227 CDD:275380 3/22 (14%)
leucine-rich repeat 228..251 CDD:275380 8/22 (36%)
LRR_8 251..310 CDD:290566 14/58 (24%)
leucine-rich repeat 252..275 CDD:275380 6/22 (27%)
leucine-rich repeat 276..299 CDD:275380 2/22 (9%)
LRR_8 299..358 CDD:290566 25/58 (43%)
leucine-rich repeat 300..323 CDD:275380 9/22 (41%)
leucine-rich repeat 324..347 CDD:275380 11/22 (50%)
leucine-rich repeat 348..372 CDD:275380 8/23 (35%)
LRR_4 373..414 CDD:289563 16/54 (30%)
LRR_8 374..433 CDD:290566 20/88 (23%)
leucine-rich repeat 375..398 CDD:275380 8/22 (36%)
leucine-rich repeat 399..420 CDD:275380 9/34 (26%)
LRRCT 433..481 CDD:214507 6/9 (67%)
Ig_3 485..572 CDD:290638
IG_like 492..586 CDD:214653
I-set 590..680 CDD:254352
Ig_1 607..681 CDD:143240
I-set 684..771 CDD:254352
IGc2 698..761 CDD:197706
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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