| Sequence 1: | NP_001246635.1 | Gene: | Con / 38590 | FlyBaseID: | FBgn0005775 | Length: | 691 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001340791.1 | Gene: | lgr4 / 558825 | ZFINID: | ZDB-GENE-111013-1 | Length: | 971 | Species: | Danio rerio |
| Alignment Length: | 675 | Identity: | 146/675 - (21%) |
|---|---|---|---|
| Similarity: | 220/675 - (32%) | Gaps: | 228/675 - (33%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 124 DENHVPVQKAECWVFSEGLHQNDTTW-----------TRFYQQKRLRELKFVIQ----------- 166
Fly 167 ----------NNARLDYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIMA 221
Fly 222 LDQDAFANHIRLRELNLEHNQIFEMDRYAFRNL-------------------------------- 254
Fly 255 ---------PLCERLF------LNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIFRGLGN 304
Fly 305 LNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERISERALDGLNTLK---TLNLRNNLLKKI 366
Fly 367 DNGLLRGTPALLSINVQANKLETLTFYTFQ----PIMDNLVNSTSELLVSDNK------------ 415
Fly 416 -------------------------------FIC------DCRLQWIFELKNRTRHLQLRDSLED 443
Fly 444 LHCTLQEPKLSHFVDPVPPTILDVLNIGGFTAIGSNSASMGGVGNSVVG------SSYSGLTMDD 502
Fly 503 S--------RKHLGSRSRQALRGQRQFASSAENVVESKMRRRRKRQEEVKEKDLAAVAPAHKRYD 559
Fly 560 YYDDNNGGMSLGHGLDLDDNLSLHKQGFYGAGSPVVGHNDVDVLMTSHSASGDALDILTTKNAIY 624
Fly 625 IKLFLLKPEMLPC---HDELSDPTE 646 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Con | NP_001246635.1 | LRR_RI | <147..291 | CDD:238064 | 42/222 (19%) |
| LRR_8 | 183..243 | CDD:290566 | 15/59 (25%) | ||
| leucine-rich repeat | 185..208 | CDD:275380 | 4/22 (18%) | ||
| leucine-rich repeat | 209..232 | CDD:275380 | 5/22 (23%) | ||
| LRR_RI | <225..416 | CDD:238064 | 64/287 (22%) | ||
| LRR_8 | 232..291 | CDD:290566 | 23/105 (22%) | ||
| leucine-rich repeat | 233..256 | CDD:275380 | 8/63 (13%) | ||
| leucine-rich repeat | 257..280 | CDD:275380 | 8/28 (29%) | ||
| leucine-rich repeat | 281..304 | CDD:275380 | 9/22 (41%) | ||
| LRR_8 | 304..363 | CDD:290566 | 22/61 (36%) | ||
| leucine-rich repeat | 305..328 | CDD:275380 | 10/22 (45%) | ||
| leucine-rich repeat | 329..352 | CDD:275380 | 6/22 (27%) | ||
| LRR_8 | 352..416 | CDD:290566 | 18/113 (16%) | ||
| leucine-rich repeat | 353..376 | CDD:275380 | 7/25 (28%) | ||
| LRRCT | 414..>450 | CDD:214507 | 11/84 (13%) | ||
| lgr4 | NP_001340791.1 | LRR 1 | 58..82 | ||
| leucine-rich repeat | 64..85 | CDD:275380 | |||
| LRR_8 | 84..144 | CDD:316378 | 2/3 (67%) | ||
| LRR 2 | 84..106 | ||||
| leucine-rich repeat | 86..109 | CDD:275380 | |||
| LRR 3 | 107..130 | ||||
| leucine-rich repeat | 110..133 | CDD:275380 | |||
| LRR 4 | 131..154 | 3/16 (19%) | |||
| leucine-rich repeat | 134..157 | CDD:275380 | 6/19 (32%) | ||
| LRR | 137..>452 | CDD:227223 | 73/317 (23%) | ||
| LRR 5 | 156..178 | 2/21 (10%) | |||
| leucine-rich repeat | 158..181 | CDD:275380 | 2/22 (9%) | ||
| LRR 6 | 179..202 | 3/22 (14%) | |||
| leucine-rich repeat | 182..205 | CDD:275380 | 2/22 (9%) | ||
| LRR 7 | 204..226 | 3/21 (14%) | |||
| leucine-rich repeat | 206..229 | CDD:275380 | 4/22 (18%) | ||
| LRR 8 | 227..250 | 5/23 (22%) | |||
| leucine-rich repeat | 230..252 | CDD:275380 | 4/22 (18%) | ||
| LRR_8 | 251..308 | CDD:316378 | 14/56 (25%) | ||
| LRR 9 | 251..273 | 6/21 (29%) | |||
| leucine-rich repeat | 253..276 | CDD:275380 | 5/22 (23%) | ||
| LRR 10 | 275..297 | 6/21 (29%) | |||
| leucine-rich repeat | 277..298 | CDD:275380 | 6/20 (30%) | ||
| LRR 11 | 299..321 | 0/21 (0%) | |||
| LRR 12 | 322..344 | 2/21 (10%) | |||
| LRR 13 | 345..366 | 6/22 (27%) | |||
| leucine-rich repeat | 348..369 | CDD:275380 | 5/22 (23%) | ||
| LRR 14 | 367..390 | 9/22 (41%) | |||
| leucine-rich repeat | 370..393 | CDD:275380 | 9/22 (41%) | ||
| LRR 15 | 391..414 | 9/22 (41%) | |||
| leucine-rich repeat | 394..415 | CDD:275380 | 9/20 (45%) | ||
| LRR 16 | 416..438 | 5/21 (24%) | |||
| leucine-rich repeat | 418..438 | CDD:275380 | 5/19 (26%) | ||
| 7tmA_LGR4 | 527..811 | CDD:320483 | 58/262 (22%) | ||
| TM helix 1 | 528..554 | CDD:320483 | 5/26 (19%) | ||
| TM helix 2 | 562..587 | CDD:320483 | 6/27 (22%) | ||
| TM helix 3 | 607..637 | CDD:320483 | 5/29 (17%) | ||
| TM helix 4 | 649..679 | CDD:320483 | 11/54 (20%) | ||
| TM helix 5 | 698..727 | CDD:320483 | 8/44 (18%) | ||
| TM helix 6 | 736..766 | CDD:320483 | 1/3 (33%) | ||
| TM helix 7 | 779..804 | CDD:320483 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C170574224 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.840 | |||||