DRSC/TRiP Functional Genomics Resources

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Protein Alignment Con and LRRC52

DIOPT Version :9

Sequence 1:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:NP_001005214.2 Gene:LRRC52 / 440699 HGNCID:32156 Length:313 Species:Homo sapiens


Alignment Length:246 Identity:61/246 - (24%)
Similarity:99/246 - (40%) Gaps:67/246 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   217 NHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPL-CERLFLNNNNISTL---HEGLFAD 277
            |:.:...|:......:|.|..|:              :|| ..|||||.|.|::|   |.||.:|
Human    28 NNCLCQAQEVICTGKQLTEYPLD--------------IPLNTRRLFLNENRITSLPAMHLGLLSD 78

  Fly   278 MARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDN-RIER 341
               |.:|:..:|:|..:....|.|:..|..|.|:.|||..|....|:.|.:|.:|.:.:| .:..
Human    79 ---LVYLDCQNNRIREVMDYTFIGVFKLIYLDLSSNNLTSISPFTFSVLSNLVQLNIANNPHLLS 140

  Fly   342 ISERALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQANKLETLTFYTFQPIMDNLVNST 406
            :.:.......:|:.|:|||..|:.:|:..|          .....|||                 
Human   141 LHKFTFANTTSLRYLDLRNTGLQTLDSAAL----------YHLTTLET----------------- 178

  Fly   407 SELLVSDNKFICDCR-LQW-----IFELKNRTRHLQLRDSLEDLHCTLQEP 451
              |.:|.|.:.|:|. |.:     :|.:          |..:||:.|..||
Human   179 --LFLSGNPWKCNCSFLDFAIFLIVFHM----------DPSDDLNATCVEP 217

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 22/77 (29%)
LRR_8 183..243 CDD:290566 5/25 (20%)
leucine-rich repeat 185..208 CDD:275380
leucine-rich repeat 209..232 CDD:275380 2/14 (14%)
LRR_RI <225..416 CDD:238064 49/195 (25%)
LRR_8 232..291 CDD:290566 20/62 (32%)
leucine-rich repeat 233..256 CDD:275380 3/22 (14%)
leucine-rich repeat 257..280 CDD:275380 12/25 (48%)
leucine-rich repeat 281..304 CDD:275380 6/22 (27%)
LRR_8 304..363 CDD:290566 17/59 (29%)
leucine-rich repeat 305..328 CDD:275380 9/22 (41%)
leucine-rich repeat 329..352 CDD:275380 3/23 (13%)
LRR_8 352..416 CDD:290566 14/63 (22%)
leucine-rich repeat 353..376 CDD:275380 8/22 (36%)
LRRCT 414..>450 CDD:214507 9/41 (22%)
LRRC52NP_001005214.2 PRK15387 <2..>93 CDD:185285 23/81 (28%)
LRRNT 26..55 CDD:214470 7/40 (18%)
leucine-rich repeat 35..54 CDD:275380 5/32 (16%)
LRR 1 54..75 9/20 (45%)
leucine-rich repeat 55..78 CDD:275380 11/22 (50%)
LRR 2 78..99 6/23 (26%)
LRR_8 79..136 CDD:338972 17/56 (30%)
leucine-rich repeat 79..102 CDD:275380 6/22 (27%)
LRR 3 102..123 8/20 (40%)
leucine-rich repeat 103..126 CDD:275380 9/22 (41%)
LRR_8 126..185 CDD:338972 16/87 (18%)
LRR 4 126..148 3/21 (14%)
leucine-rich repeat 127..151 CDD:275380 3/23 (13%)
LRR 5 151..172 8/30 (27%)
leucine-rich repeat 152..175 CDD:275380 8/32 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165141313
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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