DRSC/TRiP Functional Genomics Resources

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Protein Alignment Con and 2mit

DIOPT Version :9

Sequence 1:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:NP_001262529.1 Gene:2mit / 41616 FlyBaseID:FBgn0260793 Length:1155 Species:Drosophila melanogaster


Alignment Length:456 Identity:94/456 - (20%)
Similarity:169/456 - (37%) Gaps:155/456 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   153 YQQKR-LRELKF-VIQNNARLDY-----------------------------IPTMIIEPLKNLS 186
            ||||| .|||:. ...|...|.:                             :.::.::....|.
  Fly    81 YQQKRHKRELELNAPANKLNLTHRDLRTFNSTGGQWKGDFQVITAMDLSSNQLESLSLDNFNQLR 145

  Fly   187 SIVIEYSQVEIVK-SYAFAN--LPFLERIILNNNHIMALDQDAFANHI-RLRELNLEHNQIFEMD 247
            .:.:..:.:|::. |.|..|  |||: .:.|:.|....:....||..: :|:.|||.||::..:.
  Fly   146 QLDLGNNSLEVIPLSLADTNMSLPFV-TLDLSCNKFSQISTSFFAQRLPQLKNLNLAHNELLNIS 209

  Fly   248 RYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTR 312
            |.:|.||...:.|.|::||||.:....|..:..|.:|:|:||:::.......:|:.:|..|.:..
  Fly   210 RESFYNLLELQTLVLSHNNISDIDYETFLALPNLQYLDLSHNRLSGSAIRALQGIPDLVSLSIAY 274

  Fly   313 NNLNFIGDTVFAELWSLSELE---------------------LDDN------------------- 337
            |....:....|...|||.||:                     |.||                   
  Fly   275 NPDVGVAMQEFVASWSLKELDASGTGLCQVPAALAQSVRTLKLSDNWLKAINCGDMDSYPLLQYL 339

  Fly   338 -----RIERISERALDGLNTLKTLNLRNNLLKKIDN-------------------------GLLR 372
                 ||.::.:.||..|..|::|.|..|||.::.:                         ||:.
  Fly   340 DLSHSRIAQVEDDALGRLELLESLFLDRNLLMRVPSSLPPSLEHLFLQHNQIMELPPQAFVGLVN 404

  Fly   373 -----------------GTPALLSINVQANKLETLTFYTFQPIMDNLVNSTSELLVSDNKFICDC 420
                             ..|.||::|::::.:|:::    |.|:..| ....:||:.||...|..
  Fly   405 LQTLDLSNNRLIFLPPLSLPKLLTLNLESSGVESVS----QSIVHTL-PQLRDLLLEDNPIKCSD 464

  Fly   421 RL---QWIFELKN-----------------RTRHLQLRDSLEDL---HCTLQEPKLSHFVDPVPP 462
            .|   :|....::                 :|.:||..:..|:.   .|.:::|:    .|..||
  Fly   465 LLGIAEWASPCRSVDAGQSNGASVSGRVDLKTEYLQFHNFYENFSSRECGIRKPE----NDTKPP 525

  Fly   463 T 463
            :
  Fly   526 S 526

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 44/172 (26%)
LRR_8 183..243 CDD:290566 18/63 (29%)
leucine-rich repeat 185..208 CDD:275380 6/25 (24%)
leucine-rich repeat 209..232 CDD:275380 4/23 (17%)
LRR_RI <225..416 CDD:238064 62/278 (22%)
LRR_8 232..291 CDD:290566 22/58 (38%)
leucine-rich repeat 233..256 CDD:275380 10/22 (45%)
leucine-rich repeat 257..280 CDD:275380 7/22 (32%)
leucine-rich repeat 281..304 CDD:275380 6/22 (27%)
LRR_8 304..363 CDD:290566 21/103 (20%)
leucine-rich repeat 305..328 CDD:275380 4/22 (18%)
leucine-rich repeat 329..352 CDD:275380 11/67 (16%)
LRR_8 352..416 CDD:290566 20/105 (19%)
leucine-rich repeat 353..376 CDD:275380 8/64 (13%)
LRRCT 414..>450 CDD:214507 9/58 (16%)
2mitNP_001262529.1 LRR_RI 124..355 CDD:238064 50/231 (22%)
leucine-rich repeat 124..143 CDD:275380 0/18 (0%)
leucine-rich repeat 144..167 CDD:275380 5/22 (23%)
leucine-rich repeat 172..194 CDD:275380 4/21 (19%)
LRR_8 193..253 CDD:290566 22/59 (37%)
leucine-rich repeat 195..218 CDD:275380 10/22 (45%)
leucine-rich repeat 219..242 CDD:275380 7/22 (32%)
LRR_8 241..301 CDD:290566 15/59 (25%)
leucine-rich repeat 243..311 CDD:275380 15/67 (22%)
leucine-rich repeat 312..335 CDD:275380 3/22 (14%)
LRR_8 334..415 CDD:290566 13/80 (16%)
leucine-rich repeat 336..359 CDD:275380 5/22 (23%)
leucine-rich repeat 360..380 CDD:275380 6/19 (32%)
LRR_8 379..460 CDD:290566 14/85 (16%)
LRR_4 379..>415 CDD:289563 2/35 (6%)
leucine-rich repeat 381..404 CDD:275380 2/22 (9%)
leucine-rich repeat 405..449 CDD:275380 8/48 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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