DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Con and atk

DIOPT Version :9

Sequence 1:	NP_001246635.1	Gene:	Con / 38590	FlyBaseID:	FBgn0005775	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_001262113.1	Gene:	atk / 40266	FlyBaseID:	FBgn0036995	Length:	1535	Species:	Drosophila melanogaster

Alignment Length:	276	Identity:	71/276 - (25%)
Similarity:	132/276 - (47%)	Gaps:	8/276 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 TRFYQQKRLRELKFVIQNNARLDYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIIL 214
            |.|..|:.|..|.  :..||.||.  ::.:..|.||..|.:.|:|:..::|........:..|.|
  Fly   663 TAFDTQRSLEYLD--LSGNALLDI--SVGLGNLNNLRDIDLSYNQISRIQSDVIGGWRNVVEIRL 723

  Fly   215 NNNHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMA 279
            :||.|:.|.|..|.|..:|:.|:|..|:|..::..|.:.|...:...|.:|.:..|.:.:|.::.
  Fly   724 SNNLIVELQQGTFRNLPKLQYLDLSSNEIRNVEPGALKGLDELQEFVLADNKLVELKDHVFEELP 788

  Fly   280 RLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERISE 344
            .|...:..:|::..::.|.|....:|..|.|:.|:...:.:.....:.:|..|:|..|.::.:|.
  Fly   789 SLLASHFQYNKLRYISPESFHNANSLVFLNLSNNHFRNMENIGLRSMRNLEVLDLSTNGVKLVST 853

  Fly   345 RALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQANKLETLTFYTFQPIMDNLVNSTSEL 409
            ..|..||.|..|.:.||.:.:|........|.|..::::.|:|.::...||:.:..|:    :.|
  Fly   854 MPLKALNWLVELKMDNNQICRIQGSPFETMPRLRVLSMRNNQLRSIKERTFRNVRGNI----AIL 914

  Fly   410 LVSDNKFICDCRLQWI 425
            .|..|...|:|.:||:
  Fly   915 DVDGNPIDCNCEMQWL 930

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Con	NP_001246635.1	LRR_RI	<147..291	CDD:238064	38/140 (27%)
		LRR_8	183..243	CDD:290566	19/59 (32%)
		leucine-rich repeat	185..208	CDD:275380	5/22 (23%)
		leucine-rich repeat	209..232	CDD:275380	9/22 (41%)
		LRR_RI	<225..416	CDD:238064	44/190 (23%)
		LRR_8	232..291	CDD:290566	13/58 (22%)
		leucine-rich repeat	233..256	CDD:275380	7/22 (32%)
		leucine-rich repeat	257..280	CDD:275380	4/22 (18%)
		leucine-rich repeat	281..304	CDD:275380	4/22 (18%)
		LRR_8	304..363	CDD:290566	16/58 (28%)
		leucine-rich repeat	305..328	CDD:275380	4/22 (18%)
		leucine-rich repeat	329..352	CDD:275380	7/22 (32%)
		LRR_8	352..416	CDD:290566	15/63 (24%)
		leucine-rich repeat	353..376	CDD:275380	5/22 (23%)
		LRRCT	414..>450	CDD:214507	5/12 (42%)
atk	NP_001262113.1	leucine-rich repeat	69..89	CDD:275380
		leucine-rich repeat	90..113	CDD:275380
		leucine-rich repeat	115..138	CDD:275380
		leucine-rich repeat	139..160	CDD:275380
		leucine-rich repeat	161..184	CDD:275380
		LRR_8	183..244	CDD:290566
		leucine-rich repeat	185..209	CDD:275380
		LRR_4	209..247	CDD:289563
		leucine-rich repeat	210..233	CDD:275380
		leucine-rich repeat	234..259	CDD:275380
		LRR_RI	250..492	CDD:238064
		LRR_8	259..318	CDD:290566
		leucine-rich repeat	260..283	CDD:275380
		leucine-rich repeat	284..307	CDD:275380
		leucine-rich repeat	308..359	CDD:275380
		leucine-rich repeat	334..348	CDD:275378
		LRR_8	358..418	CDD:290566
		leucine-rich repeat	360..383	CDD:275380
		leucine-rich repeat	384..407	CDD:275380
		LRR_8	406..466	CDD:290566
		leucine-rich repeat	408..431	CDD:275380
		leucine-rich repeat	432..455	CDD:275380
		LRR_RI	447..705	CDD:238064	15/45 (33%)
		LRR_8	454..514	CDD:290566
		leucine-rich repeat	456..476	CDD:275380
		leucine-rich repeat	480..501	CDD:275380
		leucine-rich repeat	505..517	CDD:275378
		leucine-rich repeat	525..550	CDD:275380
		LRR_8	549..609	CDD:290566
		leucine-rich repeat	551..574	CDD:275380
		leucine-rich repeat	575..598	CDD:275380
		leucine-rich repeat	599..622	CDD:275380
		LRR_8	622..681	CDD:290566	6/19 (32%)
		leucine-rich repeat	623..646	CDD:275380
		LRR_RI	647..896	CDD:238064	60/236 (25%)
		leucine-rich repeat	647..670	CDD:275380	3/6 (50%)
		leucine-rich repeat	671..693	CDD:275380	7/25 (28%)
		leucine-rich repeat	694..717	CDD:275380	5/22 (23%)
		LRR_8	716..776	CDD:290566	18/59 (31%)
		leucine-rich repeat	718..741	CDD:275380	9/22 (41%)
		leucine-rich repeat	742..763	CDD:275380	6/20 (30%)
		LRR_8	765..824	CDD:290566	12/58 (21%)
		leucine-rich repeat	766..789	CDD:275380	4/22 (18%)
		leucine-rich repeat	790..813	CDD:275380	4/22 (18%)
		leucine-rich repeat	814..835	CDD:275380	4/20 (20%)
		leucine-rich repeat	838..861	CDD:275380	7/22 (32%)
		LRR_8	862..921	CDD:290566	15/62 (24%)
		leucine-rich repeat	862..885	CDD:275380	5/22 (23%)
		leucine-rich repeat	886..906	CDD:275380	5/19 (26%)
		TPKR_C2	919..>946	CDD:301599	5/12 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45617
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010