Protein Alignment Con and CG4950

DIOPT Version :10

• Sequence 1: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_648855.2
• Gene: CG4950 / 39783
• FlyBaseID: FBgn0036587
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 468
• Identity: 104/468 - (22%)
• Similarity: 180/468 - (38%)
• Gaps: 108/468 - (23%)

  Fly   114 DMKLMCYCTPDENHVPVQKAECWVFSEGLHQNDTTWTRFYQQKRL-------RELKFVIQNNARL 171
            |:.|.|.......::.|.:|.|.|         |.:|..:.|..:       ..:||:....:.|
  Fly    27 DIPLRCDEYDSMGYMDVNEAFCTV---------TGFTVTHSQNVVIKNIPPGNMVKFMKFYESTL 82

  Fly   172 DYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAF---ANLPFLERIILNNNHIMALDQDAFANHIRL 233
            .|:|..:.|....|.::.:..:.:..:...||   :||.:|.   |..|::.::....|.....|
  Fly    83 LYMPFHLFETFPYLKTLDVSNTNILELTRNAFSAASNLTYLN---LAYNNLTSIQTSVFIGANVL 144

  Fly   234 RELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEI 298
            ..|:|.:|:|..:...||..|....:::|..|.:..||..:|.|...|..::...|.:..:..|:
  Fly   145 MRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEV 209

  Fly   299 FRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIE--RISERALDGLNTLKTLNLRNN 361
            ||.:..:..:.|:.|.|.||....||:..||..|.|..|.::  :::|:     |.:..|:|.||
  Fly   210 FRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLSYNELKNFQLTEK-----NIVHQLHLDNN 269

  Fly   362 LL---------------KKIDNGLLRGTPALLSINVQANKLETLTFYTFQPIMDNLVNSTSELL- 410
            .|               .:|....|..:..:.::::.||||.:::         |:.|.|..|.
  Fly   270 YLTNLTINATRFVRASHNQISELFLHQSLHIETLDLSANKLSSIS---------NITNITHMLYL 325

  Fly   411 -VSDNKFICDCRLQWIFELKNRTRHLQLRDS---------------LEDLHCTLQEPKLSHFVDP 459
             ||||. |....:....:|| |.|.|.||.:               ||:|..:...
  Fly   326 DVSDNP-IGPLNISTFSQLK-RLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFNN--------- 379

  Fly   460 VPPTILDVLNIGGFTAIGSNSASMGGVGNSVVGSSYSGLTMDDSRKHLGSRSRQALRGQRQFASS 524
                 |.:||:..|....:|.......||        |||              .|:|.|.|:.:
  Fly   380 -----LTILNLDMFVPYLTNLKKFLIDGN--------GLT--------------ELQGNRTFSEA 417

  Fly   525 AENVVESKMRRRR 537
            ...:.:..:.|.|
  Fly   418 FPQLQKLGVSRNR 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Con	NP_523930.3	LRR	<157..459	CDD:443914	78/345 (23%)
		leucine-rich repeat	185..208	CDD:275380	5/25 (20%)
		leucine-rich repeat	209..232	CDD:275380	4/22 (18%)
		leucine-rich repeat	233..256	CDD:275380	8/22 (36%)
		leucine-rich repeat	257..280	CDD:275380	6/22 (27%)
		leucine-rich repeat	281..304	CDD:275380	5/22 (23%)
		leucine-rich repeat	305..328	CDD:275380	7/22 (32%)
		leucine-rich repeat	329..352	CDD:275380	5/24 (21%)
		leucine-rich repeat	353..376	CDD:275380	7/37 (19%)
CG4950	NP_648855.2	LRR	96..411	CDD:443914	83/369 (22%)
		leucine-rich repeat	96..119	CDD:275380	3/22 (14%)
		leucine-rich repeat	120..143	CDD:275380	5/25 (20%)
		leucine-rich repeat	144..167	CDD:275380	8/22 (36%)
		leucine-rich repeat	168..191	CDD:275380	6/22 (27%)
		leucine-rich repeat	192..215	CDD:275380	5/22 (23%)
		leucine-rich repeat	216..239	CDD:275380	7/22 (32%)
		leucine-rich repeat	240..299	CDD:275380	13/63 (21%)
		leucine-rich repeat	300..321	CDD:275380	6/29 (21%)
		leucine-rich repeat	322..345	CDD:275380	8/24 (33%)
		leucine-rich repeat	346..365	CDD:275380	4/18 (22%)
		leucine-rich repeat	370..394	CDD:275380	7/37 (19%)
		leucine-rich repeat	395..420	CDD:275380	9/46 (20%)