DRSC/TRiP Functional Genomics Resources

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Protein Alignment Con and CG5819

DIOPT Version :10

Sequence 1:NP_523930.3 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:NP_611660.1 Gene:CG5819 / 37547 FlyBaseID:FBgn0034717 Length:915 Species:Drosophila melanogaster


Alignment Length:409 Identity:102/409 - (24%)
Similarity:171/409 - (41%) Gaps:87/409 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   158 LRELKFVIQNNARLDYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIMAL 222
            ||:|.....|   ||.|.   :..|..|:.:.::.:.:.:|....|||...||.:.|:.|.:..:
  Fly   254 LRKLDVSYCN---LDSIE---LSGLPQLTEVRLQGNLLRVVDVNTFANNSMLEVVDLSQNVLRHI 312

  Fly   223 DQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLA 287
            .|||||...||:||||..|:|..:||.           |:.||::             |..|||:
  Fly   313 GQDAFAKLKRLKELNLAFNEIARLDRN-----------FIRNNDV-------------LVELNLS 353

  Fly   288 HNQINVLTSEIFRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERI-----SERAL 347
            .|.:..||..:...:..:|   ::...:..|..|..:.|..:.:|:|.:|.|..:     ||   
  Fly   354 RNVLQKLTKIVSNSVRTIN---MSWCEITSIESTALSSLSVIQKLDLSNNLITDMPTFMRSE--- 412

  Fly   348 DGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQANKLETLTFYTFQPIMDNLVNST---SEL 409
                ||:.|||.|..|..:.|...|..|.|..:::..|:|.:       ||..|..:..   .:|
  Fly   413 ----TLQQLNLANCRLTTVRNNTFREFPELADLHLNGNRLTS-------PIPPNYFDGNKFLDQL 466

  Fly   410 LVSDNKFICDCRLQWIFELKN--RTRHLQLRDSLEDLHCTLQE---PKLSHFVDPVPPTILDVLN 469
            .:.||.:||||......:..:  ..:..:::|. ..|.|....   .||..|      ...||..
  Fly   467 WLGDNPWICDCHSPLFVDFYDYLTAKPAKIKDR-NHLRCAAPAVFYGKLWEF------ACADVWI 524

  Fly   470 IGGFTAIGSNSA------SMGGVGNSVVGSSYSGLTMDDSRKHLGSRSRQALRGQRQFASSAENV 528
            :...|:.....|      ::.|:|..|:|  |:.|     :|:|  |.|:..:..|::   .|| 
  Fly   525 LNARTSSTGEKAWSIIMLTLLGLGALVLG--YACL-----QKYL--RKRKVRQSDREY---EEN- 576

  Fly   529 VESKMRRRRKRQEEVKEKD 547
             :.::||.|...|.:..::
  Fly   577 -DDELRRIRDLNERILREE 594

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_523930.3 LRR <157..459 CDD:443914 81/313 (26%)
leucine-rich repeat 185..208 CDD:275380 5/22 (23%)
leucine-rich repeat 209..232 CDD:275380 9/22 (41%)
leucine-rich repeat 233..256 CDD:275380 9/22 (41%)
leucine-rich repeat 257..280 CDD:275380 3/22 (14%)
leucine-rich repeat 281..304 CDD:275380 7/22 (32%)
leucine-rich repeat 305..328 CDD:275380 4/22 (18%)
leucine-rich repeat 329..352 CDD:275380 6/27 (22%)
leucine-rich repeat 353..376 CDD:275380 8/22 (36%)
CG5819NP_611660.1 RNA1 <56..193 CDD:444072
leucine-rich repeat 56..78 CDD:275380
leucine-rich repeat 79..102 CDD:275380
leucine-rich repeat 103..130 CDD:275380
leucine-rich repeat 131..155 CDD:275380
LRR 134..>466 CDD:443914 68/258 (26%)
leucine-rich repeat 158..182 CDD:275380
leucine-rich repeat 204..227 CDD:275380
leucine-rich repeat 254..274 CDD:275380 8/25 (32%)
leucine-rich repeat 275..298 CDD:275380 5/22 (23%)
leucine-rich repeat 299..322 CDD:275380 9/22 (41%)
leucine-rich repeat 323..346 CDD:275380 12/33 (36%)
leucine-rich repeat 347..391 CDD:275380 11/46 (24%)
leucine-rich repeat 392..413 CDD:275380 6/27 (22%)
leucine-rich repeat 414..437 CDD:275380 8/22 (36%)
LRRCT 471..517 CDD:214507 10/46 (22%)
Blue background indicates that the domain is not in the aligned region.

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