Protein Alignment Con and rk

DIOPT Version :10

• Sequence 1: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_476702.1
• Gene: rk / 34819
• FlyBaseID: FBgn0003255
• Length: 1360
• Species: Drosophila melanogaster
• Alignment Length: 713
• Identity: 148/713 - (20%)
• Similarity: 247/713 - (34%)
• Gaps: 198/713 - (27%)

  Fly    17 AICFLLLSLLLIGACLVTPTEGRAKDDRR------------------------------------ 45
            |:|.|||.|||  ..|:.|......|:.:
  Fly    12 ALCPLLLQLLL--QLLLLPPSAMGHDETKENPAPDMQNSQEQEPYVHLQHLQQQQQQNPQTVQQL 74

  Fly    46 ---TRGRGSSSGVLSSSSSSSNNM----------------NNGYYSGSSSTAGSSSGYVFTSSSA 91
               |..|.|.|..::.:....|.|                :...|.||..:..|::..|......
  Fly    75 SQITVNRTSKSASVTPTGIRENVMLPSADPEKEAQILYEKSLQEYHGSQLSTASTATDVIAGKRT 139

  Fly    92 VNSGSTGYSGPMDSTGFCTRRRDMKLMCYCTPDENHVPVQKAEC--------------WVFSEGL 142
            ::|             .|  .|.::..|:||   ..:.|.:..|              .|....|
  Fly   140 LHS-------------IC--ERWLQKHCHCT---GSLEVLRLSCRGIGILAVPVNLPNEVVVLDL 186

  Fly   143 HQNDTT---WTRFYQQKRLRELKFVIQNNARLDYIPTMI--IEPLKNLSSIVIEYSQVEIVKSYA 202
            ..|:.|   ...|:....|.||  .:.:|:.::..|...  :..||.||   ::...::.:...:
  Fly   187 GNNNLTKLEANSFFMAPNLEEL--TLSDNSIINMDPNAFYGLAKLKRLS---LQNCGLKSLPPQS 246

  Fly   203 FANLPFLERIILNNNHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNI 267
            |..|..|..:.||.|.:::||.|...:..:||.|.||.|..:.:...|...|...|.|.|.:|.:
  Fly   247 FQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLL 311

  Fly   268 STLHEGLFADMARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSEL 332
            :.:::..|..|..|..|.|..|||..:::...:.|..|.||:|..|.::.:.:.: ::|..|.||
  Fly   312 TIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGL-SKLSQLQEL 375

  Fly   333 ELDDNRIERISERALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQ-------------A 384
            .:..||:..|::..|.  .:::.|::|.|.|..|..|..||...|..:.:.             .
  Fly   376 SITSNRLRWINDTELP--RSMQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSFPELEAC 438

  Fly   385 NKLETLTF--YTFQPIMDNLVNSTSELLVSDNKF--------ICDCRLQWIFEL-KNRTRHLQLR 438
            :.||.|..  ...|.:..||...|..|...:.|.        :..||...:.:| .|:...:|.:
  Fly   439 HALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRIPNLSSCRDLRLLDLSSNQIEKIQGK 503

  Fly   439 -----DSLEDLHCTLQE------------PKLSHFVDPVPPTILDVLN----------IGGFTAI 476
                 ..|.||..:...            |||.         :||:..          ..||||:
  Fly   504 PFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQ---------LLDLEGNEISYIHKEAFSGFTAL 559

  Fly   477 GSNSASMGGVGNSVVGS-SYSGLTMDDSRKHLGSRSRQALRG----------QRQFASSAEN--- 527
            ...:     :||::... ..|||.   :..||.:.:...||.          |....|.|.:
  Fly   560 EDLN-----LGNNIFPELPESGLR---ALLHLKTFNNPKLREFPPPDTFPRIQTLILSYAYHCCA 616

  Fly   528 ----VVESKMRRRRKRQEEVKEKDLAAVAPAHKRYDYYDDNNGGMSLG---HGLDLDDNLSLH 583
                |..|..::..:.||       |.:.|:...:|....||..|::.   |.|......|:|
  Fly   617 FLPLVAMSSQKKTSQVQE-------AVLFPSDAEFDMTLWNNSMMNIWPQMHNLSKQLGASMH 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Con	NP_523930.3	LRR	<157..459	CDD:443914	81/344 (24%)
		leucine-rich repeat	185..208	CDD:275380	4/22 (18%)
		leucine-rich repeat	209..232	CDD:275380	7/22 (32%)
		leucine-rich repeat	233..256	CDD:275380	8/22 (36%)
		leucine-rich repeat	257..280	CDD:275380	6/22 (27%)
		leucine-rich repeat	281..304	CDD:275380	7/22 (32%)
		leucine-rich repeat	305..328	CDD:275380	6/22 (27%)
		leucine-rich repeat	329..352	CDD:275380	7/22 (32%)
		leucine-rich repeat	353..376	CDD:275380	8/22 (36%)
rk	NP_476702.1	LRR	<157..390	CDD:443914	58/238 (24%)
		leucine-rich repeat	158..179	CDD:275380	2/20 (10%)
		leucine-rich repeat	183..204	CDD:275380	4/20 (20%)
		leucine-rich repeat	205..228	CDD:275380	5/24 (21%)
		leucine-rich repeat	229..252	CDD:275380	6/25 (24%)
		leucine-rich repeat	253..276	CDD:275380	7/22 (32%)
		leucine-rich repeat	277..300	CDD:275380	8/22 (36%)
		LRR	292..612	CDD:443914	74/339 (22%)
		leucine-rich repeat	301..324	CDD:275380	6/22 (27%)
		leucine-rich repeat	325..348	CDD:275380	7/22 (32%)
		leucine-rich repeat	349..371	CDD:275380	6/22 (27%)
		leucine-rich repeat	372..393	CDD:275380	7/22 (32%)
		leucine-rich repeat	394..415	CDD:275380	7/20 (35%)
		leucine-rich repeat	418..486	CDD:275380	11/67 (16%)
		leucine-rich repeat	441..464	CDD:275378	7/22 (32%)
		leucine-rich repeat	487..510	CDD:275380	3/22 (14%)
		leucine-rich repeat	511..534	CDD:275380	3/22 (14%)
		leucine-rich repeat	535..558	CDD:275380	5/31 (16%)
		leucine-rich repeat	559..580	CDD:275380	5/28 (18%)
		7tmA_Glyco_hormone_R	754..1028	CDD:320264
		TM helix 1	755..781	CDD:320264
		TM helix 2	788..813	CDD:320264
		TM helix 3	833..863	CDD:320264
		TM helix 4	875..897	CDD:320264
		TM helix 5	918..947	CDD:320264
		TM helix 6	956..986	CDD:320264
		TM helix 7	996..1021	CDD:320264