DRSC/TRiP Functional Genomics Resources

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Protein Alignment Con and CG42346

DIOPT Version :9

Sequence 1:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:NP_001036303.2 Gene:CG42346 / 3355160 FlyBaseID:FBgn0259677 Length:1817 Species:Drosophila melanogaster


Alignment Length:578 Identity:141/578 - (24%)
Similarity:234/578 - (40%) Gaps:131/578 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   156 KRLRELKFVIQNNARLDYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIM 220
            |.||||..:..::.|:..:...:.|..|.|.::.:.::.:..:.. .|:|||.|..:.|:.|:|:
  Fly   505 KSLRELMSLDMSHNRIIGLDPKVFEKNKRLQTVDLSHNHIHTIGG-VFSNLPQLREVFLSENNIL 568

  Fly   221 ALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLN 285
            .|..|||.|...:..:.||.|.|..:|...|..|...:.|:|.:|.|..|...||....:||.|:
  Fly   569 ELPADAFTNSTNVDVIYLESNAIAHIDPNVFSTLVNLDHLYLRSNFIPLLPVTLFDKSTKLTSLS 633

  Fly   286 LAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERISERALDGL 350
            |.:|:|..|...:||.|.:|..::|..|.:..:...||..|.||.||.:..|.||.|..:|...|
  Fly   634 LDNNEIQDLEIGMFRKLEHLREVRLHNNRIRRVRRGVFEPLPSLQELHIQKNSIEDIEPQAFHTL 698

  Fly   351 NTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQAN---KLETLTFYTFQPIM-----DNLVN--- 404
            ..::.:||::|.|..:::.......:|||:.::||   |:...||...|.:.     ||.:.   
  Fly   699 ENMQHINLQDNQLTVLEDIFPDENSSLLSVQLEANYLHKVHPRTFSRQQKVQIMWLKDNQLTRVE 763

  Fly   405 --------STSELLVSDNK--------FICDCRLQWIFELKNRTRHLQLRD------SLEDLHC- 446
                    ....|.:||||        |:....||::....|:.|.|: ||      .||:|.. 
  Fly   764 RSFFADTPQLGRLYLSDNKIRDIEKDTFVNLLLLQFLDLSGNQLRQLR-RDYFAPLQDLEELSLA 827

  Fly   447 ----------------TLQEPKLSHFVDPVPPTILDVLNIGGFTAIGSNSASMGGVGNSVVGSSY 495
                            .|:...|||  :|:.....|:.         ||...:    ||:     
  Fly   828 RNHIEAIEGYAFAKLKNLKSLDLSH--NPLVQLTRDIF---------SNEFPL----NSL----- 872

  Fly   496 SGLTMDDSRKHLGSRSRQALRGQRQFASSAENVVESKMRRRRKRQEEVKEKD---LAAVAPAHKR 557
                      :||:.|.:.|. |..| .|..|:.|..:.|.:....:::..|   |..:..:|..
  Fly   873 ----------NLGNCSLRKLE-QHAF-KSLTNLNELNLERNQLNPADIQTLDIPNLRRLLLSHNN 925

  Fly   558 YDYYDDNNGGMSLGHGLDLDDNLSLHKQGFYGAGSPVVGHNDVDVLMTSHSASGDALDILTTKNA 622
            :.|    .|.:.:..|: ||...||.:                  |..|:.:.|...|:|..||.
  Fly   926 FSY----AGSVGIMAGM-LDRLRSLQQ------------------LSMSNCSLGQIPDLLFAKNT 967

  Fly   623 IYIKLFL-----------------LKPEMLPCHDELSDPTELPL----SRDLMDVRSN 659
            ..::|.|                 :..|:..|.:||||...:.|    :.:.:|:..|
  Fly   968 NLVRLDLCDNRLTQINRNIFSGLNVFKELRLCRNELSDFPHIALYNLSTLESLDLARN 1025

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 41/134 (31%)
LRR_8 183..243 CDD:290566 18/59 (31%)
leucine-rich repeat 185..208 CDD:275380 4/22 (18%)
leucine-rich repeat 209..232 CDD:275380 9/22 (41%)
LRR_RI <225..416 CDD:238064 64/217 (29%)
LRR_8 232..291 CDD:290566 19/58 (33%)
leucine-rich repeat 233..256 CDD:275380 7/22 (32%)
leucine-rich repeat 257..280 CDD:275380 7/22 (32%)
leucine-rich repeat 281..304 CDD:275380 10/22 (45%)
LRR_8 304..363 CDD:290566 19/58 (33%)
leucine-rich repeat 305..328 CDD:275380 6/22 (27%)
leucine-rich repeat 329..352 CDD:275380 9/22 (41%)
LRR_8 352..416 CDD:290566 20/90 (22%)
leucine-rich repeat 353..376 CDD:275380 4/22 (18%)
LRRCT 414..>450 CDD:214507 14/66 (21%)
CG42346NP_001036303.2 leucine-rich repeat 303..325 CDD:275380
LRR_8 325..384 CDD:290566
leucine-rich repeat 327..350 CDD:275380
leucine-rich repeat 351..461 CDD:275380
LRR_8 373..433 CDD:290566
LRR_RI 397..648 CDD:238064 43/143 (30%)
leucine-rich repeat 399..422 CDD:275380
leucine-rich repeat 462..485 CDD:275380
LRR_8 465..520 CDD:290566 5/14 (36%)
leucine-rich repeat 486..509 CDD:275380 2/3 (67%)
LRR_8 508..567 CDD:290566 14/59 (24%)
leucine-rich repeat 510..533 CDD:275380 3/22 (14%)
LRR_RI 527..785 CDD:238064 76/258 (29%)
leucine-rich repeat 534..556 CDD:275380 4/22 (18%)
LRR_8 555..613 CDD:290566 19/57 (33%)
leucine-rich repeat 557..580 CDD:275380 9/22 (41%)
leucine-rich repeat 581..604 CDD:275380 7/22 (32%)
LRR_8 604..663 CDD:290566 20/58 (34%)
leucine-rich repeat 605..628 CDD:275380 7/22 (32%)
leucine-rich repeat 629..652 CDD:275380 10/22 (45%)
LRR_8 652..711 CDD:290566 19/58 (33%)
leucine-rich repeat 653..676 CDD:275380 6/22 (27%)
leucine-rich repeat 677..700 CDD:275380 9/22 (41%)
leucine-rich repeat 701..748 CDD:275380 12/46 (26%)
leucine-rich repeat 725..736 CDD:275378 5/10 (50%)
leucine-rich repeat 749..772 CDD:275380 2/22 (9%)
LRR_8 771..831 CDD:290566 16/60 (27%)
leucine-rich repeat 773..793 CDD:275380 6/19 (32%)
LRR_RI 804..1076 CDD:238064 56/278 (20%)
LRR_8 821..903 CDD:290566 23/113 (20%)
leucine-rich repeat 821..844 CDD:275380 3/22 (14%)
leucine-rich repeat 845..868 CDD:275380 8/33 (24%)
leucine-rich repeat 869..892 CDD:275380 9/43 (21%)
leucine-rich repeat 893..915 CDD:275380 3/21 (14%)
leucine-rich repeat 916..944 CDD:275380 7/32 (22%)
leucine-rich repeat 945..968 CDD:275380 8/40 (20%)
LRR_8 967..1027 CDD:290566 11/59 (19%)
leucine-rich repeat 969..992 CDD:275380 2/22 (9%)
leucine-rich repeat 993..1014 CDD:275380 7/20 (35%)
LRR_8 1015..1075 CDD:290566 2/11 (18%)
leucine-rich repeat 1017..1040 CDD:275380 2/9 (22%)
leucine-rich repeat 1041..1064 CDD:275380
LRR_RI <1047..1244 CDD:238064
LRR_8 1063..1125 CDD:290566
leucine-rich repeat 1089..1114 CDD:275380
leucine-rich repeat 1115..1162 CDD:275380
LRR_8 1163..1219 CDD:290566
leucine-rich repeat 1163..1186 CDD:275380
leucine-rich repeat 1187..1210 CDD:275380
leucine-rich repeat 1211..1233 CDD:275380
leucine-rich repeat 1234..1257 CDD:275380
LRR_8 1235..1292 CDD:290566
leucine-rich repeat 1258..1279 CDD:275380
leucine-rich repeat 1282..1306 CDD:275380
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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